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Merck
CN

B-069

Supelco

Bupropion System Suitability Mix solution

12-20 μg/mL (80:20 0.001N HCl:Methanol), certified reference material, ampule of 1 mL, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C7H5O2Cl
Molecular Weight:
156.57
UNSPSC Code:
41116107
NACRES:
NA.24

Key Documents

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grade

certified reference material

feature

Snap-N-Spike®/Snap-N-Shoot®

composition

3-Chlorobenzoic Acid, 12 μg/mL
1-(3-Chlorophenyl)-1-Hydroxy-2-Propanone, 20 μg/mL
1-(3-Chlorophenyl)-2-Hydroxypropan-1-one, 20 μg/mL

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

12-20 μg/mL (80:20 0.001N HCl:Methanol)

format

multi-component solution

shipped in

wet ice

storage temp.

−20°C

General description

Bupropion belongs to the group of antidepressant drugs and is commonly used for the management of depressive disorders and in non-nicotine anti-depressant therapy for quitting smoking. It has been proposed that its mode of action in combating smoking involves changing systems related to both the dopamine and norepinephrine neurotransmitters.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Flam. Liq. 3 - STOT SE 1

Target Organs

Eyes,Central nervous system

WGK

WGK 2

Regulatory Information

危险化学品
This item has

Certificates of Analysis (COA)

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A comparison of sustained-release bupropion and placebo for smoking cessation
Hurt RD, et al.
The New England Journal of Medicine, 337(17), 1195-1202 (1997)
15 years of clinical experience with bupropion HCl: from bupropion to bupropion SR to bupropion XL
Fava M, et al.
Primary care companion to the Journal of clinical psychiatry, 7(3), 106-106 (2005)
Bupropion is a nicotinic antagonist
Slemmer JE, et al.
Journal of Pharmacology and Experimental Therapeutics, 295(1), 321-327 (2000)

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