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Merck
CN

T-904

Trimipramine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C20H26N2
CAS Number:
739-71-9
Molecular Weight:
294.43
NACRES:
NA.24
PubChem Substance ID:
329826892
UNSPSC Code:
41116107
MDL number:
MFCD00242595

Key Documents

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InChI

1S/C20H26N2/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22/h4-11,16H,12-15H2,1-3H3

SMILES string

CN(C)CC(C)CN1C2=C(C=CC=C2)CCC3=C1C=CC=C3

InChI key

ZSCDBOWYZJWBIY-UHFFFAOYSA-N

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

2-8°C

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), DRD2(1813), HRH1(3269), HTR2A(3356), HTR2C(3358), SLC6A2(6530)

General description

Trimipramine is a tricyclic antidepressant prescribed for treatment of depression, insomnia, and chronic pain or as an adjunctive therapy for alcohol or opioid withdrawal. This certified solution standard is applicable for use in clinical toxicology, forensic analysis, or urine drug testing applications by LC-MS/MS or GC/MS. Trimipramine is marketed under the trade names Surmontil®, Rhotrimine, and Stangyl.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Surmontil is a registered trademark of Pliva, Inc.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Regulatory Information

危险化学品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Donald F Smith et al.
Psychopharmacology, 195(1), 131-138 (2007-07-27)
Molecular tools are needed for assessing anti-depressant actions by positron emission tomography (PET) in the living human brain. This study determined whether [(11)C]mirtazapine is an appropriate molecular tool for use with PET to estimate the magnitude of neuroreceptor occupancy produced
Britta Haenisch et al.
Psychopharmacology, 217(2), 289-295 (2011-04-13)
The antidepressant trimipramine shows an atypical pharmacological profile and its mechanism of action is still obscure. The present study investigated whether trimipramine and three of its metabolites interact with targets of other antidepressants, namely, the human monoamine transporters for noradrenaline
M T Jafari et al.
Analytical and bioanalytical chemistry, 399(10), 3555-3564 (2011-02-08)
A novel method based on three-phase hollow fiber microextraction technique (HF-LPME) coupled with electrospray ionization-ion mobility spectrometry (ESI-IMS) was developed for the simultaneous determination of two antidepressant drugs (trimipramine and desipramine) in urine and plasma samples. The effects of various
Diansong Zhou et al.
Drug metabolism and disposition: the biological fate of chemicals, 38(5), 863-870 (2010-02-06)
The role of human UDP glucuronosyltransferase (UGT) 2B10 in the N-glucuronidation of a number of tricyclic antidepressants was investigated and compared with that of UGT1A4 in both the Sf9 expressed system and human liver microsomes. The apparent K(m) (S(50)) values
M Flechtner-Mors et al.
Journal of psychiatric research, 42(7), 578-586 (2007-08-19)
The intake of antidepressants is often accompanied by weight gain. Antidepressants may influence lipid and carbohydrate metabolism that can result in metabolic changes and obesity. We investigated the effect of citalopram and trimipramine on interstitial glycerol, glucose and lactate concentration
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