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Merck
CN

V-017

Nicotinic acid (Vitamin B3) solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

Nicotinic acid, Vitamin B3, 3-Picolinic acid, Niacin, Pellagra preventive factor, Pyridine-3-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C6H5NO2
CAS Number:
59-67-6
Molecular Weight:
123.11
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329828960
EC Number:
200-659-6
Beilstein/REAXYS Number:
109591
MDL number:
MFCD00006391

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InChI

1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

InChI key

PVNIIMVLHYAWGP-UHFFFAOYSA-N

SMILES string

OC(=O)c1cccnc1

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

mp

236-239 °C (lit.)

density

0.791 g/cm3 at 20 °C

format

single component solution

storage temp.

−20°C

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General description

Nicotinic acid, also known as niacin, is a water-soluble vitamin of the B complex and essential human nutrient. Niacin deficiency, often the result of impaired nutritional status associated with conditions ranging from malnutrition to chronic alcoholism, is monitored in patient plasma samples by HPLC. This Certified Spiking Solution® is suitable for use as a starting material in the preparation of linearity standards, calibrators or controls in a variety of testing applications from diagnostic testing of niacin deficiency by HPLC to quality control testing of niacin-based pharmaceutical preparations, dietary supplements, or fortified foods.

Legal Information

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

Regulatory Information

危险化学品
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Certificates of Analysis (COA)

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N Nakajima et al.
Clinical toxicology (Philadelphia, Pa.), 51(5), 451-454 (2013-05-07)
Erythromelalgia is a rare disorder characterized by reddening, severe burning pain, and swelling of the extremities. Food poisoning by Clitocybe acromelalga, a poisonous mushroom, is known to induce erythromelalgia; however, its treatment protocol remains unclear. We describe here three cases
Rachel L Edwards et al.
Infection and immunity, 81(3), 945-955 (2013-01-16)
In response to environmental fluctuations or stresses, bacteria can activate transcriptional and phenotypic programs to coordinate an adaptive response. The intracellular pathogen Legionella pneumophila converts from a noninfectious replicative form to an infectious transmissive form when the bacterium encounters alterations
Niacin therapy lives for another day-maybe?
Carl J Lavie et al.
Journal of the American College of Cardiology, 61(21), 2197-2198 (2013-04-02)
Drugs for hypertriglyceridemia.
The Medical letter on drugs and therapeutics, 55(1411), 17-19 (2013-03-08)
Wanda C Lakey et al.
Journal of clinical lipidology, 7(2), 178-181 (2013-02-19)
Multiple cholesterol-reducing therapies have been shown to induce the regression of tendon xanthoma in patients with familial hypercholesterolemia. We present 3 cases of adverse reactions in Achilles tendon xanthomas after the addition of niacin and bile acid sequestrants to ongoing
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