Name: H-Gly-Arg-Gly-Asp-Ser-OH - CAS 96426-21-0 - Calbiochem
Brand: MM

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About This Item

Empirical Formula (Hill Notation):

C₁₇H₃₀N₈O₉

CAS Number:

96426-21-0

Molecular Weight:

490.47

MDL number:

MFCD00076459

UNSPSC Code:

12352202

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Assay

≥97% (HPLC)

Quality Level

100

form

lyophilized solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white to off-white

solubility

5% acetic acid: 1 mg/mL
water: 1 mg/mL

shipped in

ambient

storage temp.

−20°C

InChI

1S/C17H30N8O9/c18-5-11(27)23-8(2-1-3-21-17(19)20)14(31)22-6-12(28)24-9(4-13(29)30)15(32)25-10(7-26)16(33)34/h8-10,26H,1-7,18H2,(H,22,31)(H,23,27)(H,24,28)(H,25,32)(H,29,30)(H,33,34)(H4,19,20,21)/t8-,9-,10-/m0/s1

InChI key

RGNVSYKVCGAEHK-GUBZILKMSA-N

General description

A cell binding protein domain. Competitively inhibits direct binding of fibroblasts to fibronectin. In mice it has been shown to prevent bladder tumor cell implantation. Also, reported to inhibit the migration of vascular smooth muscle cells into fibrin gels.

Biochem/physiol Actions

Cell permeable: no

Primary Target
fibroblast binding

Product does not compete with ATP.

Reversible: no

Physical form

Supplied as an acetate salt.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Kodama, M., et al. 2002. Life Sci.71, 1139.
Hyacinthe, L.M., et al. 1995. Ann. Surg. Oncol.2, 450.
Pierschbacher, M.D., and Ruoslahti, E. 1984. Nature309, 30.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Certificates of Analysis (COA)

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