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Merck
CN

04-638

Anti-TRF1 Antibody, clone BED5 57-6

clone BED5 57-6, Upstate®, from mouse

Synonym(s):

TERF1, telomeric repeat binding factor (NIMA-interacting) 1, FLJ41416, PIN2, TRBF1, TRF, TRF1, hTRF1-AS, t-TRF1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
BED5 57-6, monoclonal
Application:
IF, WB
Citations:
2
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

BED5 57-6, monoclonal

species reactivity

mouse, rat, hamster, monkey, human

packaging

antibody small pack of 25 μg

manufacturer/tradename

Upstate®

technique(s)

immunofluorescence: suitable, western blot: suitable

isotype

IgG1κ

NCBI accession no.

UniProt accession no.

shipped in

ambient

target post-translational modification

unmodified

Gene Information

human ... TERF1(7013)

General description

~60 kDa

Immunogen

Human TRF1 protein

Application

This Anti-TRF1 Antibody, clone BED5 57-6 is validated for use in WB, IF for the detection of TRF1.

Biochem/physiol Actions

Detects TRF1

Physical form

Affinity purified immunoglobulin in PBS with 0.05% NaN3
Format: Purified

Analysis Note

Routinely evaluated by Western Blot on HeLa cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany


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Regulatory Information

动物来源生物产品
常规特殊物品
低风险生物材料

This item has



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Related Content

"Recognizing both the tremendous opportunities and the challenges facing cancer research, we are dedicated to developing and refining tools and technologies for the study of cancer. With our comprehensive portfolio, including the Upstate®, Chemicon®, and Calbiochem® brands of reagents and antibodies, researchers can count on dependable, high quality solutions for analyzing all the hallmarks of cancer."


PTOP and TRF1 help enhance the radio resistance in breast cancer cell.
Li, Z; Yang, X; Xia, N; Yang, L; Yu, H; Zhou, F; X, C; Zhou, Y
Cancer Cell International null
Emily Mason-Osann et al.
EMBO reports, 21(6), e49495-e49495 (2020-04-28)
Cancer cells can activate the alternative lengthening of telomeres (ALT) pathway to promote replicative immortality. The ALT pathway promotes telomere elongation through a homologous recombination pathway known as break-induced replication (BIR), which is often engaged to repair single-ended double-stranded breaks



Global Trade Item Number

SKUGTIN
04-638-25UG04054839350139