05-164
Anti-PLCβ-1 Antibody
Upstate®, from mouse
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
monoclonal
Application:
immunoprecipitation (IP)
Species reactivity:
rat, mouse, bovine, human
Citations:
24
Technique(s):
immunoprecipitation (IP): suitable
Uniprot accession no.:
Product Name
Anti-PLCβ-1 Antibody, Upstate®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
monoclonal
species reactivity
rat, mouse, bovine, human
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PLCB1(23236)
Analysis Note
routinely evaluated by immunoprecipition of PLCβ-1 from a bovine brain membrane preparation, subsequent immunoblotting performed by the antibody
Application
Detect PLCβ-1 using this Anti-PLCβ-1 Antibody validated for use in IP.
Research Category
Signaling
Signaling
Research Sub Category
Lipid Signaling
Lipid Signaling
Biochem/physiol Actions
PLCβ-1, also recognize the 100kDa and 41kDa fragments of PLCβ-1.1
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
150 kDa
Immunogen
Mixed monoclonal antibodies raised against purified bovine PLCβ-1
Physical form
100mM Tris-glycine, pH 7.4, 0.15M NaCl with 0.05% sodium azide
Format: Purified
Protein G Chromatography
Preparation Note
2 years at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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N Liu et al.
The Journal of biological chemistry, 271(1), 355-360 (1996-01-05)
To discover a new phospholipase C (PLC) related to cell growth, we screened a cDNA library prepared from regenerating rat liver. A novel PLC (PLC delta 4) encoding a polypeptide of 770 amino acids with structural similarity to PLC delta-type
Roberta Fiume et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(3), 957-966 (2008-11-26)
Inositide-specific phospholipase Cbeta1 (PLCbeta1) signaling in cell proliferation has been investigated thoroughly in the G(1) cell cycle phase. However, little is known about its involvement in G(2)/M progression. We used murine erythroleukemia cells to investigate the role of PLCbeta1 in
Hideki Igarashi et al.
Developmental biology, 312(1), 321-330 (2007-10-27)
Inositol 1,4,5-trisphosphate generated by the action of a phospholipase C (PLC) mediates release of intracellular Ca2+ that is essential for sperm-induced activation of mammalian eggs. Much attention currently focuses on the role of sperm-derived PLCzeta in generating changes in egg
Phospholipase C-beta1 is present in the botrysome, an intermediate compartment-like organelle, and Is regulated by visual experience in cat visual cortex
Kind, P. C., et al
The Journal of Neuroscience, 17, 1471-1480 (1997)
Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage.
Christmann, M; Tomicic, MT; Aasland, D; Berdelle, N; Kaina, B
Nucleic Acids Research null
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