05-517
Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1
clone 3D1.1, Upstate®, from mouse
Synonym(s):
Anti-BDE2, Anti-HHM, Anti-PLP, Anti-PTHR, Anti-PTHRP
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
3D1.1, monoclonal
species reactivity
pig, human, mouse
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... PTHLH(5744)
General description
80 kDa; receptor dimer at 160 kDa
Immunogen
Synthetic peptide corresponding to amino acids 146-169 of the human PTH/PTHrP (parathyroid hormone/parathyroid hormone related protein) receptor (RRCDRNGSWELVPGHNRTWANYSE).
Application
Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1 is an antibody against PTH/PTHrP Receptor for use in IH & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Hormones & Receptors
Hormones & Receptors
Biochem/physiol Actions
Recognizes PTH/PTHrP receptor and the receptor dimer.
Physical form
Format: Purified
Protein G Purified
Protein G Purified immunoglobulin in Immunoaffinity Purified immunoglobulin in 0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Preparation Note
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
Kidney Tissue
Kidney Tissue
Routinely evaluated by immunoblot on RIPA lysates of 3T3-L1 pre-adipose fibroblasts
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Qi Zhu et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 28(9), 1898-1911 (2013-05-30)
To assess the effect of hypoparathyroidism on osteogenesis and bone turnover in vivo, bone marrow ablation (BMXs) were performed in tibias of 8-week-old wild-type and parathyroid hormone-null (PTH(-/-)) mice and newly formed bone tissue was analyzed from 5 days to
Christine V Marzan et al.
Developmental biology, 349(2), 125-136 (2010-10-27)
We generated a transgenic (Tg)-mouse model expressing a dominant negative-(DN)-RARα, (RARαG303E) under adipocytes-specific promoter to explore the paracrine role of adipocyte retinoic acid receptors (RARs) in mammary morphogenesis. Transgenic adipocytes had reduced level of RARα, β and γ, which coincided
Altered ovarian function affects skeletal homeostasis independent of the action of follicle-stimulating hormone.
Gao, J; Tiwari-Pandey, R; Samadfam, R; Yang, Y; Miao, D; Karaplis, AC; Sairam, MR; Goltzman, D
Endocrinology null
Cell-specific effects of nitric oxide deficiency on parathyroid hormone-related peptide (PTHrP) responsiveness and PTH1 receptor expression in cardiovascular cells.
Rolf Schreckenberg, Sibylle Wenzel, Rui Manuel da Costa Rebelo, Anja Rothig, Rainer Meyer et al.
Endocrinology null
Joachim Albers et al.
The Journal of cell biology, 192(6), 1057-1072 (2011-03-16)
Although Wnt signaling in osteoblasts is of critical importance for the regulation of bone remodeling, it is not yet known which specific Wnt receptors of the Frizzled family are functionally relevant in this process. In this paper, we show that
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