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Merck
CN

07-002

Anti-p67-phox Antibody

serum, Upstate®

Synonym(s):

Anti-NCF-2, Anti-NOXA2, Anti-P67-PHOX, Anti-P67PHOX

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_000433

UniProt accession no.

P19878

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... NCF2(4688)

General description

65kDa

Immunogen

GST fusion protein corresponding to full-length human p67-phox.

Application

Research Category
Neuroscience
Research Sub Category
Oxidative Stress
This Anti-p67-phox Antibody is validated for use in IP, WB, IC for the detection of p67-phox.

Biochem/physiol Actions

p67-phox

Physical form

Antiserum
rabbit antiserum containing 0.05% azide

Preparation Note

2 years at -20°C

Analysis Note

routinely evaluated by immunoblot on RIPA lysates from HL-60 cells

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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INF-? Enhances Nox2 Activity by Upregulating phox Proteins When Applied to Differentiating PLB-985 Cells but Does Not Induce Nox2 Activity by Itself.
Ellison, MA; Thurman, G; Gearheart, CM; Seewald, RH; Porter, CC; Ambruso, DR
Testing null
Aicha Bouraoui et al.
Free radical biology & medicine, 199, 113-125 (2023-02-25)
Poldip2 was shown to be involved in oxidative signaling to ensure certain biological functions. It was proposed that, in VSMC, by interaction with the Nox4-associated membrane protein p22phox, Poldip2 stimulates the level of reactive oxygen species (ROS) production. In vitro
Tara E Scott et al.
Scientific reports, 13(1), 19589-19589 (2023-11-11)
In cardiovascular disease, pathological and protective roles are reported for the Th2 cytokines IL-4 and IL-13, respectively. We hypothesised that differential effects on macrophage function are responsible. Type I and II receptor subunit (IL-2Rγ, IL-4Rα and IL-13Rα1) and M2 marker
Martin de Boer et al.
Human mutation, 35(4), 486-496 (2014-01-31)
Retrotransposon-mediated insertion of a long interspersed nuclear element (LINE)-1 or an Alu element into a human gene is a well-known pathogenic mechanism. We report a novel LINE-1-mediated insertion of a transcript from the TMF1 gene on chromosome 3 into the
D Roos et al.
Clinical and experimental immunology, 175(2), 139-149 (2013-09-11)
Patients with chronic granulomatous disease (CGD) suffer from recurrent, life-threatening bacterial and fungal infections of the skin, the airways, the lymph nodes, liver, brain and bones. Frequently found pathogens are Staphylococcus aureus, Aspergillus species, Klebsiella species, Burkholderia cepacia and Salmonella
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