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Merck
CN

07-300

Anti-Cofilin 2 Antibody

Upstate®, from rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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Product Name

Anti-Cofilin 2 Antibody, Upstate®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... CFL2(1073)

Analysis Note

routinely evaluated by immunoblot on RIPA lysates from rat L6 cell lysates

Application

Research Category
Cell Structure
Research Sub Category
Cytoskeleton
This Anti-Cofilin 2 Antibody is validated for use in WB for the detection of Cofilin 2.

Biochem/physiol Actions

Cofilin 2

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

21kDa

Immunogen

peptide corresponding to amino acids 136-152 (C-QVNGLDDIKDRSTLGEK) of human Cofilin 2

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A chromatography

Preparation Note

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 1


Certificates of Analysis (COA)

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Stromal cell-derived factor 1alpha activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis.
Nishita, Michiru, et al.
Molecular and cellular biology, 22, 774-783 (2002)
Live imaging of Drosophila melanogaster neural stem cells with photo-ablated centrosomes.
Thomas, et al.
STAR protocols, 3, 101493-101493 (2022)
Mitosis-dependent phosphorylation and activation of LIM-kinase 1.
Sumi, Tomoyuki, et al.
Biochemical and biophysical research communications, 290, 1315-1320 (2002)
Mark Manzano et al.
RNA (New York, N.Y.), 21(9), 1606-1620 (2015-07-04)
Sequence heterogeneity at the ends of mature microRNAs (miRNAs) is well documented, but its effects on miRNA function are largely unexplored. Here we studied the impact of miRNA 5'-heterogeneity, which affects the seed region critical for target recognition. Using the
Mardjaneh Sadegh Karbalaei et al.
European journal of pharmacology, 689(1-3), 179-185 (2012-05-31)
Caveolae are membrane invaginations present in a variety of cell types. Formation of caveolae depends on caveolins and on the more recently discovered family of proteins known as the cavins. Genetic ablation of caveolin-1 was previously shown to give rise

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