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Merck
CN

07-728

Anti-HRI Antibody

serum, Upstate®

Synonym(s):

Anti-HCR, Anti-HRI, Anti-LEMSPAD, Anti-hHRI

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
18
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rabbit, human, mouse

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... EIF2AK1(27102)
mouse ... Eif2Ak1(15467)

General description

72kDa

Immunogen

6His-tagged fusion protein corres-ponding to residues 1-138 of mouse heme-regulated inhibitor (HRI)

Application

Detect HRI using this Anti-HRI Antibody validated for use in IP & WB.

Biochem/physiol Actions

HRI

Analysis Note

Routinely evaluated by immunoblot on lysates from mouse reticulocytes.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J J Chen et al.
Trends in biochemical sciences, 20(3), 105-108 (1995-03-01)
Protein synthesis is regulated by the phosphorylation of the alpha-subunit of eukaryotic initiation factor 2 (eIF-2 alpha) in a variety of cells. At present, there are two distinct mammalian eIF-2 alpha kinases that have been cloned, the double-stranded-RNA-dependent eIF-2 alpha
Takahiro Sakai et al.
Antioxidants (Basel, Switzerland), 10(9) (2021-09-29)
Lung fibrosis is the primary pathology in idiopathic pulmonary fibrosis and is considered to result from an increase in reactive oxygen species (ROS) levels in alveolar epithelial cells. However, the exact mechanism underlying lung fibrosis remains unclear and there is
The eIF-2alpha kinases and the control of protein synthesis.
de Haro, C, et al.
Faseb Journal, 10, 1378-1387 (1996)



Global Trade Item Number

SKUGTIN
07-72804053252404092