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Merck
CN

1.17480

Ethanol

greener alternative

BioRenewable, ≥99.9% (GC), suitable for LC-MS, LiChrosolv®

Synonym(s):

Ethyl alcohol

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About This Item

Linear Formula:
CH3CH2OH
CAS Number:
Molecular Weight:
46.07
UNSPSC Code:
12191502
NACRES:
NA.03
EC Index Number:
200-578-6
MDL number:
Beilstein/REAXYS Number:
1718733
Assay:
≥99.9% (GC)
Bp:
78 °C (lit.)
Vapor pressure:
128 hPa ( 20 °C), 410 mmHg ( 50 °C), 44.6 mmHg ( 20 °C), 97.68 mmHg ( 20 °C)
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Quality Level

vapor density

1.59 (vs air)

vapor pressure

128 hPa ( 20 °C), 410 mmHg ( 50 °C), 44.6 mmHg ( 20 °C), 97.68 mmHg ( 20 °C)

product line

LiChrosolv®

assay

≥99.9% (GC)

form

liquid

autoignition temp.

683 °F

expl. lim.

19 %, 60 °F

greener alternative product characteristics

Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

refractive index

n20/D 1.3600 (lit.), n/D (n20/D 1.3600)(lit.)

pH

7.0 (20 °C, 10 g/L in H2O)

bp

78 °C (lit.)

mp

−114 °C (lit.)

transition temp

flash point 12 °C

suitability

suitable for HPLC, suitable for LC-MS

application(s)

(LC/MS, PFAS Testing)

greener alternative category

SMILES string

CCO

InChI

1S/C2H6O/c1-2-3/h3H,2H2,1H3

InChI key

LFQSCWFLJHTTHZ-UHFFFAOYSA-N

General description

This bio-based solvent for LC-MS offers the same precision and reliability you trust, now with more sustainability.

  • Derived from renewable feedstocks with bio-carbon content certification
  • Similar chromatographic resolution, reproducibility, and baseline stability
  • Drop-in replacement: no method redevelopment required
We are committed to bringing you greener alternative products that adhere to one or more of the 12 Principles of Greener Chemistry, and this bio-based (BioRenewable) product aligns with the principles of Safer Solvents and Auxiliaries and Use of Renewable Feedstocks.

LiChrosolv® hypergrade is accurately tested for LC-MS suitability and meets all the requirements of modern LC-MS ionization methods (ESI/APCI - positive and negative mode). Thanks to their low level of ionic background and low ion suppression, LiChrosolv® hypergrade solvents provide high reproducibility and high ionization efficiency. The packaging material has been improved to meet LC-MS quality requirements perfectly.

Application

  • Mobile Phase in HPLC-MS: Ethanol is an effective polar solvent in high-performance liquid chromatography-mass spectrometry (HPLC-MS), facilitating the separation and detection of a diverse range of analytes, including pharmaceuticals and environmental contaminants.
  • Gradient Elution: Ideal for gradient elution techniques in HPLC, ethanol enhances resolution and separation efficiency of complex mixtures, making it particularly beneficial for analyzing intricate samples in pharmaceutical and environmental studies.
  • Pharmaceutical Analysis: Essential for the analysis of drug formulations and metabolites, ethanol is used in HPLC-MS for stability testing, impurity profiling, and pharmacokinetic studies, ensuring compliance with regulatory standards.

Features and Benefits

  • High Purity: Formulated with ultra-high purity to minimize impurities, ensuring reliable and reproducible results crucial for sensitive LC-MS applications.
  • Excellent Mass Spectrometric Compatibility: Optimized for compatibility with various ionization techniques in LC-MS, enhancing sensitivity and accuracy in detection.
  • Low Background Noise: Reduces background interference, leading to cleaner spectra and improved signal-to-noise ratios, essential for detecting trace-level analytes.
  • Consistent Quality Assurance: Batch-to-batch consistency guarantees uniform quality and performance, fostering confidence in analytical results and reproducibility across experiments.
  • Versatile Solvent Properties: Its unique solvent characteristics make it suitable for a wide range of applications, from routine analyses to complex method development, providing flexibility in laboratory settings.

Other Notes

1Distribution and use of ethyl alcohol in Switzerland require a license from the Swiss Federal Alcohol Administration
Distribution and use of ethyl alcohol in Switzerland require a license from the Swiss Federal Alcohol Administration.
Bio-Based LC-MS Solvents

LiChrosolv® bio-based solvents are derived from renewable feedstocks and verified through bio-carbon content certification. They provide comparable chromatographic performance to conventional solvents; same resolution, reproducibility, and baseline stability; and function as drop-in replacements requiring no method redevelopment.

Available with Data Matrix Code

This high-quality LCMS-grade solvent now features a unique Data Matrix Code on its label, providing digital access to essential product information such as batch number, product number, and expiry date. Unlike standard barcodes, our DMCs feature a unique serial number for each bottle, enabling you to monitor and trace every bottle individually. With standard barcodes, all bottles from the same batch look identical. Our solution gives you true bottle-level traceability for greater control and compliance in the lab.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany


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pictograms

FlameExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

55.4 °F - closed cup

flash_point_c

13 °C - closed cup

Regulatory Information

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Certificates of Analysis (COA)

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