1.04771
Acetonitrile
BioRenewable, gradient grade for liquid chromatography LiChrosolv® Reag. Ph Eur
Synonym(s):
ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide, Anhydrous ACN, Dry MeCN
Select a Size
About This Item
vapor density
1.41 (vs air)
vapor pressure
72.8 mmHg ( 20 °C)
description
at 200 nm, ≤0.1
from 240 nm, ≤0.01
product line
LiChrosolv®
grade
gradient grade, gradient grade (for liquid chromatography LiChrosolv® Reag. Ph Eur)
assay
≥99.9% (GC)
form
liquid
autoignition temp.
973 °F
expl. lim.
16 %
greener alternative product characteristics
Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
impurities
≤0.0002 meq/g Acidity, ≤0.0002 meq/g Alkalinity, ≤0.02% Water
transmittance
193 nm, ≥60%, 195 nm, ≥80%, 230 nm, ≥98%
refractive index
n20/D 1.344 (lit.), n/D (n/D 1.344
n20/D 1.344 (lit.))
bp
81-82 °C (lit.)
mp
−45 °C (lit.)
transition temp
flash point 2 °C
density
0.786 g/mL at 25 °C (lit.)
format
neat
greener alternative category
storage temp.
2-30°C
SMILES string
CC#N
InChI
1S/C2H3N/c1-2-3/h1H3
InChI key
WEVYAHXRMPXWCK-UHFFFAOYSA-N
General description
- Derived from renewable feedstocks with bio-carbon content certification
- Similar chromatographic resolution, reproducibility, and baseline stability
- Drop-in replacement: no method redevelopment required
LiChrosolv® solvents are specially formulated to meet the demanding needs of analytical HPLC applications. With exceptional UV transmittance, minimal particle count, and controlled acidity and alkalinity, our solvents ensure reproducible separations every time. The low evaporation residue level further enhances their performance, making them the ideal choice for high-quality results. The product line includes both "gradient grade" and "isocratic grade" solvents, specifically designed to reduce the gradient effect during separations. This tailored approach allows for optimal consistency and accuracy in your analytical processes, helping you achieve the best possible outcomes in your chromatography work.
Application
- Reversed-Phase HPLC: Commonly used as a mobile phase component for the separation of a wide range of compounds, including pharmaceuticals, environmental pollutants, and biomolecules.
- Gradient Elution: Ideal for gradient elution techniques, enhancing the resolution and separation efficiency of complex mixtures.
- Pharmaceutical Analysis: Frequently employed in the analysis of active pharmaceutical ingredients (APIs) and their impurities, ensuring compliance with regulatory standards.
- Biological Sample Analysis: Used for the analysis of proteins, peptides, and metabolites in biological samples, facilitating accurate quantification and identification.
- Environmental Monitoring: Applied in the HPLC analysis of environmental samples to detect and quantify contaminants in water, soil, and air.
Features and Benefits
- High Purity: Formulated with minimal impurities, ensuring reliable and reproducible results essential for sensitive analytical applications.
- Excellent UV Transparency: Provides optimal UV transmittance, facilitating accurate detection and enhancing sensitivity in HPLC analyses.
- Low Evaporation Residue: Minimizes contamination risk, leading to cleaner separations and improved analytical reliability.
- Batch-to-Batch Consistency: Ensures uniform quality and performance across different production batches, enhancing reproducibility, and confidence in analytical results.
Other Notes
LiChrosolv® bio-based solvents are derived from renewable feedstocks and verified through bio-carbon content certification. They provide comparable chromatographic performance to conventional solvents; same resolution, reproducibility, and baseline stability; and function as drop-in replacements requiring no method redevelopment.
Available with Data Matrix Code
This high-quality LCMS-grade solvent now features a unique Data Matrix Code on its label, providing digital access to essential product information such as batch number, product number, and expiry date. Unlike standard barcodes, our DMCs feature a unique serial number for each bottle, enabling you to monitor and trace every bottle individually. With standard barcodes, all bottles from the same batch look identical. Our solution gives you true bottle-level traceability for greater control and compliance in the lab.
Legal Information
Still not finding the right product?
Explore all of our products under Acetonitrile
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
Storage Class
3 - Flammable liquids
flash_point_f
35.6 °F - closed cup
flash_point_c
2.0 °C - closed cup
Regulatory Information
This item has
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.