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Sigma-Aldrich

PKC Substrate Peptide 2

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eCl@ss:
32160405
NACRES:
NA.42

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

NM_002737.2

UniProt accession no.

P17252

shipped in

dry ice

Gene Information

human ... PRKCA(5578)

Biochem/physiol Actions

Protein Target: PKC
Target Sub-Family: AGC

Quality

Routinely evaluated as a substrate for PKC Epsilon (14-236), PKC Zeta (14-235) and MST2 activity (14-417).

Physical form

Lyophilized powder

Storage and Stability

Lyophilized: 2 years at -20°C; Rehydrated: 6 months at -20°C.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(C)

Not applicable

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Expression, purification, and characterization of protein kinase C-epsilon
Schaap, D. and Parker, P. J.
The Journal of Biological Chemistry, 265, 7301-7307 (1990)
D Schaap et al.
FEBS letters, 243(2), 351-357 (1989-01-30)
PKC-epsilon was isolated from a murine brain cDNA library. The clone, lambda 61PKC-epsilon, encoded a polypeptide of 737 amino acids that is homologous to other PKCs. Northern analysis showed that the 7 kb mRNA for this cDNA is widely expressed.
H L Lai et al.
The Journal of biological chemistry, 272(8), 4970-4977 (1997-02-21)
We have previously reported that phosphorylation of adenylyl cyclase type VI (AC6) may result in the suppression of adenylyl cyclase activity during desensitization of the A2a-adenosine receptor-mediated cAMP response (A2a desensitization) in rat pheochromocytoma PC12 cells. In the present study

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