14-632-M
TSSK2 Protein, active, 10 µg
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.32
description
protein target TSSK2
Quality Level
purified by
(Ni2+/NTA-agarose)
technique(s)
activity assay: suitable
UniProt accession no.
Gene Information
human ... TSSK2(23617)
General description
44.8kDa
FUNCTION: SwissProt: Q96PF2 # Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm (By similarity).
COFACTOR: Magnesium (By similarity).
SIZE: 358 amino acids; 40939 Da
SUBUNIT: Binds to STK22A (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
TISSUE SPECIFICITY: Testis.
PTM: Autophosphorylated (By similarity).
DISEASE: SwissProt: Q96PF2 # May play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. Most cases result from a deletion of chromosome 22q11.2 (the DiGeorge syndrome chromosome region, or DGCR).
SIMILARITY: SwissProt: Q96PF2 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
COFACTOR: Magnesium (By similarity).
SIZE: 358 amino acids; 40939 Da
SUBUNIT: Binds to STK22A (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
TISSUE SPECIFICITY: Testis.
PTM: Autophosphorylated (By similarity).
DISEASE: SwissProt: Q96PF2 # May play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. Most cases result from a deletion of chromosome 22q11.2 (the DiGeorge syndrome chromosome region, or DGCR).
SIMILARITY: SwissProt: Q96PF2 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 protein kinase domain.
Packaging
Also available in 10 μg size (cat#14-632) and in bulk (cat#14-632-K).
Preparation Note
6 months at -70°C
Analysis Note
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Routinely evaluated by phosphorylation of CHKtide
routinely evaluated by phosphorylation of CHKtide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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