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218841

InSolution Caspase-9 Inhibitor I - Calbiochem

Name: InSolution Caspase-9 Inhibitor I - Calbiochem
Brand: MM

The InSolution Caspase-9 Inhibitor I controls the biological activity of Caspase-9. This small molecule/inhibitor is primarily used for Cancer applications.

Synonym(s):

InSolution Caspase-9 Inhibitor I - Calbiochem, Z-LE(OMe)HD(OMe)-FMK

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About This Item

Empirical Formula (Hill Notation):

C₃₂H₄₃FN₆O₁₀

Molecular Weight:

690.72

UNSPSC Code:

12352200

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form

liquid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic), protect from light

shipped in

wet ice

storage temp.

−20°C

General description

A 5 mM (250 µg/72 µl) solution of Z-LEHD-FMK (Cat. No. 218761) in DMSO. A potent, cell-permeable, and irreversible inhibitor of caspase-9 (ICE-LAP6, Mch6).

Biochem/physiol Actions

Cell permeable: yes

Primary Target
caspase-4, caspase-5, caspase-9

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Physical form

A 5 mM solution of Z-LEHD-FMK (Cat. No. 218761) in DMSO.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

single spot by TLC

Other Notes

Fadeel, B., et al. 1999. Leukemia13, 719.

Z-Leu-Glu(OMe)-His-Asp(OMe)-CH₂F*

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - (refers to pure substance)

flash_point_c

87 °C - (refers to pure substance)

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

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