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Merck
CN

324900

(−)-Epinephrine (+)-bitartrate salt

α,β-Adrenergic receptor agonist.

Synonym(s):

L-(–)-Epinephrine-(+)-bitartrate, 1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanol, Adrenaline Bitartrate

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About This Item

Empirical Formula (Hill Notation):
C9H13NO3 · xC4H6O6
CAS Number:
Molecular Weight:
183.20 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥95% (TLC)
Form:
solid
Storage condition:
OK to freeze, desiccated (hygroscopic)
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Product Name

L-(–)-Epinephrine-(+)-bitartrate, α,β-Adrenergic receptor agonist.

Quality Segment

description

Merck USA index - 14, 3619

assay

≥95% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic)

color

white

solubility

ethanol: soluble, water: soluble

shipped in

ambient

storage temp.

2-8°C

SMILES string

N(C[C@H](O)c1cc(c(cc1)O)O)C.O[C@H]([C@@H](O)C(=O)O)C(=O)O

InChI

1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1

InChI key

YLXIPWWIOISBDD-NDAAPVSOSA-N

General description

α,β-Adrenergic receptor agonist. Has positive chronotropic and inotropic effects on heart muscle. Activates adenylate cyclase to generate cAMP from ATP.
An α,β-adrenergic receptor agonist. Has positive chronotropic and inotropic effects on cardiac muscle. Its major actions are mediated via activation of adenylate cyclase. Enhances mitochondrial oxidation of substrates.

Biochem/physiol Actions

Cell permeable: no
Primary Target
α,β-Adrenergic receptor agonist
Product does not compete with ATP.
Reversible: no

Preparation Note

Unstable in solution; reconstitute just prior to use.

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Oudit, G.Y., and Butler, D.G. 1995. Am. J. Physiol.268, R1273.
Mohan, C., et al. 1991. Arch. Biochem. Biophys.287, 18.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Highly Toxic & Carcinogenic / Teratogenic (I)


pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 1 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
324900-100MG07790788049195