362338
Glyco-SNAP-1 - Calbiochem
A water-soluble nitric oxide (NO) donor.
Synonym(s):
Glyco-SNAP-1 - Calbiochem, N-(β-D-Glucopyranosyl)-N²-acetyl-S-nitroso-D,L-penicillaminamide
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About This Item
Empirical Formula (Hill Notation):
C13H23N3O8S
Molecular Weight:
381.40
UNSPSC Code:
12352200
Quality Segment
assay
≥96% (NMR)
form
crystalline solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
green
solubility
aqueous buffer: 100 mg/mL, water: 100 mg/mL, methanol: 5 mg/mL
shipped in
ambient
storage temp.
−20°C
General description
A water-soluble and stable nitric oxide (NO) donor (t½ = 28.5-30.2 hr). Glyco-SNAP-1 is more stable than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8-9). The SNAP moiety acts as an NO group donor and the sugar fragment provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes much more slowly in the presence of thiols such as cysteine or glutathione.
A water-soluble nitric oxide (NO) donor. More stable (t½ = 28.5-30.2 hr) than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8 - 9). The SNAP moiety acts as an NO group donor and the sugar moiety provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes at a much slower rate in the presence of thiols such as cysteine or glutathione.
Biochem/physiol Actions
Cell permeable: no
Primary Target
A water-soluble nitric oxide (NO) donor
A water-soluble nitric oxide (NO) donor
Product does not compete with ATP.
Reversible: no
Preparation Note
Unstable in solution; reconstitute just prior to use.
Other Notes
Hou, Y., et al. 1999. Methods Enzymol. 301, 242.
Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett.6, 2575.
Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett.6, 2575.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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