407271
Integrin αMβ2 Ligand - CAS 307525-40-2 - Calbiochem
Synonym(s):
Integrin αMβ₂ Ligand - CAS 307525-40-2 - Calbiochem
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About This Item
Empirical Formula (Hill Notation):
C19H15NOS2
CAS Number:
Molecular Weight:
337.46
UNSPSC Code:
12352200
MDL number:
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
yellow
solubility
DMSO: 15 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
A cell-permeable thioxothiazolidine compound that displays anti-inflammatory properties. Shown to increase cell adhesion and lowers leukemia cell migration in vitro and leukocyte recruitment in vivo and displays anti-inflammatory properties. Binds to and stabilizes integrin αM I domain active conformation and enhances the ligands′ (pro-MMP-9 and fibrinogen) binding ability.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
Binds to and stabilizes integrin αM I domain active conformation
Binds to and stabilizes integrin αM I domain active conformation
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Other Notes
Bjorklund, M., et al. 2006. Biochemistry45, 2862.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
10-13 - German Storage Class 10 to 13
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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