445825
DL-2-Mercaptomethyl-3-guanidinoethylthiopropanoic Acid - Calbiochem
Synonym(s):
Plummer’s Inhibitor
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General description
Potent reversible inhibitor of human plasma carboxypeptidase N (Ki = 2 nM).
Potent reversible inhibitor of human plasma carboxypeptidase N (Ki = 2 nM). Inhibits hydrolysis of bradykinin.
Biochem/physiol Actions
Target IC50:2 nM against human plasma carboxypeptidase N
Preparation Note
Addition of a small amount of NaOH or NH₄OH may be necessary to achieve complete solubilization.
Unstable in solution; reconstitute just prior to use.
Storage Class
10-13 - German Storage Class 10 to 13
Regulatory Information
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A potent mercapto bi-product analogue inhibitor for human carboxypeptidase N.
T H Plummer et al.
Biochemical and biophysical research communications, 98(2), 448-454 (1981-01-30)