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475914

Nystatin

Name: Nystatin
Brand: MM

from Streptomyces noursei, ≥95% (sum of two peaks, HPLC), solid, sodium ionoph, Calbiochem^®

Synonym(s):

Nystatin, Streptomyces noursei, Mycostatin

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About This Item

Empirical Formula (Hill Notation):

C₄₇H₇₅NO₁₇

CAS Number:

1400-61-9

Molecular Weight:

926.09

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD25541651

Assay:

≥95% (sum of two peaks, HPLC)

Form:

solid

Quality level:

100

Storage condition:

OK to freeze, protect from light

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Properties

Product Name

Nystatin, Streptomyces noursei, A polyene antifungal antibiotic effective against yeast and mycoplasma.

Quality Level

100

description

Merck USA index - 14, 6736

assay

≥95% (sum of two peaks, HPLC)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, protect from light

color

off-white to yellow

solubility

DMSO: 50 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

N[C@@H]1[C@@H]([C@H](O[C@@H]([C@H]1O)C)OC2CC3O[C@@](CC(C3C(=O)O)O)(CC(C(CCC(CC(CC(CC(=O)O[C@H]([C@@H]([C@@H]([C@H](\C=C\C=C\CC\C=C\C=C\C=C\C=C\2)C)O)C)C)O)O)O)O)O)O)O

InChI

1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31?,32?,33?,34?,35?,36?,37?,38?,40?,41-,42+,43+,44-,46+,47+/m0/s1

InChI key

VQOXZBDYSJBXMA-RKEBNKJGSA-N

Description

General description

A polyene antifungal antibiotic effective against yeast and mycoplasma. Induces loss of low molecular weight substances from cells with low selectivity. A cation selective ionophore that exhibits selectivity for Na⁺. Increases the activity of the Na⁺-K⁺ pump. Suggested concentration is 50 µg/ml.

Biochem/physiol Actions

Potency: ≥3000 units/mg (anhydrous).

Other Notes

Gruwel, M.L., et al. 1995. Am J. Physiol.268, H351.
Opekarova, M., and Tanner, W. 1994. FEBS Lett. 360, 46.
Stoos, B.A., et al. 1994. J. Am. Soc. Nephrol.4, 1855.
Skolink, P.R., et al. 1989. J. Infect. Dis.160, 1056.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c