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5.05415

Sigma-Aldrich

Cyclothiazide

Synonym(s):

Cyclothiazide

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About This Item

Empirical Formula (Hill Notation):
C14H16ClN3O4S2
CAS Number:
2259-96-3
Molecular Weight:
389.88
MDL number:
MFCD00210192
UNSPSC Code:
12352200

Assay

≥98% (sum of two diastereoisomers, HPLC)

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

white

solubility

DMSO: 100 mM
ethanol: 25 mM

storage temp.

2-8°C

InChI

1S/C14H16ClN3O4S2/c15-10-5-11-13(6-12(10)23(16,19)20)24(21,22)18-14(17-11)9-4-7-1-2-8(9)3-7/h1-2,5-9,14,17-18H,3-4H2,(H2,16,19,20)

InChI key

BOCUKUHCLICSIY-UHFFFAOYSA-N

General description

Selectively blocks AMPA receptor desensitization and potentiates AMPA and kainate-induced increases in intracellular calcium and norepinephrine release.

Biochem/physiol Actions

Primary Target
AMPA receptor

Warning

Toxicity: Irritant (B)

Other Notes

David, J., et al. 1996. J. Neurosci.16, 200.
Lijequist, S., et al. 1995. Biochem. Pharmacol.50, 1761.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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