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520224

PPACK, Dihydrochloride, Biotinylated

Potent inhibitor of thrombin and tissue plasminogen activator (tPA). Useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.

Synonym(s):

PPACK, Dihydrochloride, Biotinylated, Biotin-X-D-Phe-Pro-Arg-chloromethylketone, 2HCl

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About This Item

Empirical Formula (Hill Notation):
C43H70ClN10O7S · 2HCl
Molecular Weight:
979.52
UNSPSC Code:
12352200
Assay:
≥80% (HPLC and TLC)
Form:
liquid
Quality level:
100
Storage condition:
OK to freeze, avoid repeated freeze/thaw cycles
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Quality Level

100

assay

≥80% (HPLC and TLC)

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

shipped in

wet ice

storage temp.

−20°C

General description

Biotin-X-analog of Cat. No. 520222. Specific probe for active serine proteases. Potent inhibitor of thrombin and tissue plasminogen activator (tPA). Useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.
Biotin-X-analog of Cat. No. 520222. Specific probe for active serine proteases. Potent inhibitor of thrombin and tissue plasminogen activator (tPA). Useful for Western blot analyses of Factor VIIa, Factor XIa, thrombin, and tPA.

Biochem/physiol Actions

Cell permeable: no
Product does not compete with ATP.
Reversible: no
Target IC50: 110 nM against thrombin

Physical form

In 10 mM HCl.

Other Notes

Williams, E.B., et al. 1989. J. Biol. Chem.264, 7536.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Storage Class

12 - Non Combustible Liquids

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Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
520224-1MG04055977271317