539582
PSA Substrate, Fluorogenic - Calbiochem
An excellent fluorogenic substrate for assaying the proteolytic activity of prostate-specific antigen (PSA).
Synonym(s):
PSA Substrate, Fluorogenic - Calbiochem, Mu-HSSKLQ-AFC, 2TFA, Prostate Specific Antigen Substrate, Fluorogenic
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About This Item
Empirical Formula (Hill Notation):
C44H60F3N12O13 · xC2H4O2
Molecular Weight:
1022.02 (free base basis)
UNSPSC Code:
12352200
assay
≥90% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
white
solubility
DMSO: 20 mg/mL
fluorescence
λex 400 nm, λem 505 nm
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
An excellent fluorogenic substrate for assaying the proteolytic activity of prostate-specific antigen (PSA).
An excellent fluorogenic substrate for assaying the proteolytic activity of prostate-specific antigen (PSA). Has an excitation maximum of 400 nm and an emission maximum of 505 nm.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Fluorogenic substrate for assaying the proteolytic activity of prostate-specific antigen (PSA)
Fluorogenic substrate for assaying the proteolytic activity of prostate-specific antigen (PSA)
Product does not compete with ATP.
Reversible: no
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Recommended reaction buffer: 400 μM substrate in 50 mM Tris-HCl, pH 7.9, 10 mM NaCl.
Other Notes
Denmeade, S.R., et al. 1997. Cancer Res. 57, 4924.
Mu-His-Ser-Ser-Lys-Leu-Gln-AFC, 2TFA (Mu = morpholinoureidyl)
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
10-13 - German Storage Class 10 to 13
Certificates of Analysis (COA)
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