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Merck
CN

539582

PSA Substrate, Fluorogenic - Calbiochem

An excellent fluorogenic substrate for assaying the proteolytic activity of prostate-specific antigen (PSA).

Synonym(s):

PSA Substrate, Fluorogenic - Calbiochem, Mu-HSSKLQ-AFC, 2TFA, Prostate Specific Antigen Substrate, Fluorogenic

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About This Item

Empirical Formula (Hill Notation):
C44H60F3N12O13 · xC2H4O2
Molecular Weight:
1022.02 (free base basis)
UNSPSC Code:
12352200
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Quality Level

assay

≥90% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated (hygroscopic)

color

white

solubility

DMSO: 20 mg/mL

fluorescence

λex 400 nm, λem 505 nm

shipped in

ambient

storage temp.

−20°C

General description

An excellent fluorogenic substrate for assaying the proteolytic activity of prostate-specific antigen (PSA).
An excellent fluorogenic substrate for assaying the proteolytic activity of prostate-specific antigen (PSA). Has an excitation maximum of 400 nm and an emission maximum of 505 nm.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Fluorogenic substrate for assaying the proteolytic activity of prostate-specific antigen (PSA)
Product does not compete with ATP.
Reversible: no

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).
Recommended reaction buffer: 400 μM substrate in 50 mM Tris-HCl, pH 7.9, 10 mM NaCl.

Other Notes

Denmeade, S.R., et al. 1997. Cancer Res. 57, 4924.
Mu-His-Ser-Ser-Lys-Leu-Gln-AFC, 2TFA (Mu = morpholinoureidyl)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


Storage Class

10-13 - German Storage Class 10 to 13



Certificates of Analysis (COA)

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