Skip to Content
Merck
CN

559307

Sigma-Aldrich

Sangivamycin - CAS 18417-89-5 - Calbiochem

Synonym(s):

Sangivamycin - CAS 18417-89-5 - Calbiochem, 7-Deaza-7-carbamoyladenosine, NSC-65346

Sign Into View Organizational & Contract Pricing

Select a Size

About This Item

Empirical Formula (Hill Notation):
C12H15N5O5
CAS Number:
18417-89-5
Molecular Weight:
309.28
MDL number:
MFCD00214391
UNSPSC Code:
12352200

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Assay

≥98% (HPLC)

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

solubility

0.1 M KOH: 5 mg/mL

shipped in

ambient

storage temp.

2-8°C

InChI

1S/C12H15N5O5/c13-9-6-4(10(14)21)1-17(11(6)16-3-15-9)12-8(20)7(19)5(2-18)22-12/h1,3,5,7-8,12,18-20H,2H2,(H2,14,21)(H2,13,15,16)

InChI key

OBZJZDHRXBKKTJ-UHFFFAOYSA-N

General description

This product has been discontinued.



A cytotoxic purine nucleoside active against human cytomegalovirus (HCMV). A cell-permeable, reversible, selective, and potent protein kinase C (PKC) inhibitor (IC50 = 10 µM). The inhibition is competitive with respect to ATP and non-competitive with respect to histone and lipid cofactors.

A cytotoxic purine nucleoside active against human cytomegalovirus (HCMV). A cell-permeable, reversible, selective, and potent protein kinase C (PKC) inhibitor (IC50 = 10 µM). The inhibition is competitive with respect to ATP and non-competitive with respect to histone and lipid cofactors.

Biochem/physiol Actions

Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Target IC50: 10 µM against PKC

Other Notes

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Greene, N.M., et al. 1995. J. Biol. Chem. 270, 6710.
Osada, H., et al. 1989. J. Antibiot. 42, 402.
Loomis, C.R. and Bell, R.M. 1988. J. Biol. Chem. 263, 1682.
Turk, S.R., et al. 1987. Antimicrob. Agents Chemother. 31, 544.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Highly Toxic (H)

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Regulatory Information

新产品
This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service