570100
Ste11 MAPKKK Activation Inhibitor - CAS 331662-51-2 - Calbiochem
The Ste11 MAPKKK Activation Inhibitor, also referenced under CAS 331662-51-2, controls the biological activity of Ste11 MAPKKK.
Synonym(s):
Ste11 MAPKKK Activation Inhibitor - CAS 331662-51-2 - Calbiochem, 4-((2,4-Dichlorophenyl)amino)-6,7-dimethoxyquinazoline
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About This Item
Empirical Formula (Hill Notation):
C16H13Cl2N3O2
CAS Number:
Molecular Weight:
350.20
UNSPSC Code:
12352200
assay
≥97% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
DMSO: 10 mg/mL, ethanol: 5 mg/mL
shipped in
ambient
Quality Level
General description
A quinazolinamine PD 153035 (Cat. No. 234490) analog that inhibits Ste11 signaling and c-Abl tyrosine kinase activity in yeast. Also reported to inhibit Src kinase activity with an IC50 of 250 nM.
A quinazolinamine PD 153035 (Cat. No. 234490) analog that inhibits Ste11 signaling and c-Abl tyrosine kinase activity in yeast. Also reported to inhibit Src kinase activity with an IC50 of 250 nM.
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Kitagawa, T., et al. 2007. Biosci. Biotechnol. Biochem.71, 772.
Boschelli, D.H., et al. 2001. J. Med. Chem.44, 822.
Boschelli, D.H., et al. 2001. J. Med. Chem.44, 822.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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