573112
SPDP
Synonym(s):
Succinimidyl 3-(2-pyridyldithio)propionate
assay
≥95% (HPLC)
form
solid
color
off-white
solubility
DMF: 10 mg/mL
General description
A heterobifunctional cross-linker. Reagent similar to SATA, useful for introducing protected thiol groups into a variety of proteins. Treatment with DTT releases the chromophore 2-pyridylthione and a mercaptopropionyl-modified amine. This thiolated biomolecule can then be coupled to a second biomolecule through an iodoacetamide or maleimide group. In addition, the thiolated biomolecule can be reacted with a second pyridyldisulfide-containing biomolecule.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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