6.02444
Chloroform
suitable for chromatography
Synonym(s):
Chloroform, Methylidyne trichloride, Trichloromethane
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About This Item
Empirical Formula (Hill Notation):
CHCl3
CAS Number:
Molecular Weight:
119.38
UNSPSC Code:
12191502
Beilstein/REAXYS Number:
1731042
MDL number:
InChI key
HEDRZPFGACZZDS-UHFFFAOYSA-N
SMILES string
ClC(Cl)Cl
InChI
1S/CHCl3/c2-1(3)4/h1H
vapor density
4.1 (vs air)
vapor pressure
160 mmHg ( 20 °C)
Quality Level
mp
−63 °C (lit.)
suitability
suitable for chromatography
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General description
Chloroformis used as an extraction solvent in the dispersive liquid-liquid microextraction(DLLME) technique. It is also used as a mobile phase in the columnchromatography method.
Application
- Preparation and application of stimuli-responsive PET TeMs: Utilizes RAFT graft block copolymerisation of styrene and acrylic acid for the separation of water-oil emulsions, demonstrating the adaptation of chloroform in enhancing polymer properties for environmental applications (Muslimova et al., 2024).
- Effect of Stool Sampling on a Routine Clinical Method: Describes the use of chloroform in gas chromatography-mass spectrometry for the quantification of short-chain fatty acids in stool samples, highlighting its importance in clinical diagnostics (Mahdi et al., 2024).
- Improved lipid analysis using a 2D-LC-MS system: Discusses a novel injection procedure involving chloroform for enhanced lipid profiling, showcasing its critical role in advanced biochemical analysis (Pánczél et al., 2024).
- Ecological Risk Assessment of Three Pesticide Additives in Soil: Addresses the application of chloroform in the remediation of contaminated soils, emphasizing its utility in environmental toxicology and soil science (Li et al., 2024).
Regulatory Information
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Development of a dispersive liquid--liquid microextraction method for the determination of fluoroquinolones in chicken liver by high performance liquid chromatography
Moema D, et al.
Analytica Chimica Acta, 730, 80-86 (2012)
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