616455
TGF-β1, Human, Recombinant, CHO Cell Line
Synonym(s):
rhTGF-β1, Transforming Growth Factor-β1
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About This Item
UNSPSC Code:
12352202
Manufacturer/tradename:
Calbiochem®
assay
≥97% (SDS-PAGE)
Quality Segment
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
≤1 EU/μg Endotoxin (EU/μg TGF-β1)
shipped in
ambient
storage temp.
−20°C
General description
Recombinant, human transforming growth factor-β1 expressed in CHO cells. Promotes apoptosis in resting human B lymphocytes, glioma cells, and trigeminal neurinomal cells. Induces the accumulation of extracellular matrix in various diseases.
Biochem/physiol Actions
ED₅₀ = 0.04-0.1 ng/ml
Physical form
Lyophilized from a sterile filtered solution in 50 µg BSA/µg TGF-β1, 35% acetonitrile, 0.1% TFA.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 3 months at -20°C.
Reconstitute to a concentration ≥1 µg/ml in 4 mM sterile HCl containing ≥0.1% HSA or BSA.
Other Notes
Shibuya, H., et al. 1996. Science272, 1179.
Bottlinger, E.P., et al. 1995. Proc. Natl. Acad. Sci. USA93, 5877.
Lomo, J., et al. 1995. J. Immunol.154, 1634.
Marushige, K., and Marushige, Y. 1995. Anticancer Res.14, 2419.
Yamazaki, M., et al. 1994. Am. J. Pathol. 144, 221.
Bottlinger, E.P., et al. 1995. Proc. Natl. Acad. Sci. USA93, 5877.
Lomo, J., et al. 1995. J. Immunol.154, 1634.
Marushige, K., and Marushige, Y. 1995. Anticancer Res.14, 2419.
Yamazaki, M., et al. 1994. Am. J. Pathol. 144, 221.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Storage Class
11 - Combustible Solids
wgk
WGK 3
Certificates of Analysis (COA)
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