PRG4, Proteoglycan 4, is a human gene and is found in synovial tissue, cartilage, and liver. Small amounts are found in the lung. Isoform 1 is found in the kidney, lung, liver, heart and brain. The other Isoforms, C & D, are widely expressed. PRG4 is a lubricating glycoprotein containing chondroitin sulfate and keratan sulfate glycosaminoglycans. It is responsible for boundary lubrication at the cartilage surface. A disease associated with PRG4 is Jacobs’s syndrome which is an autosomal recessive disorder.

~37 kDa

Epitope: C-Teminus

KLH-conjugated followed by PRG4 corresponding to the C-terminal region

Anti-PRG4 Antibody is an antibody against PRG4 for use in WB & IC.

Immunocytochemistry:
Confocal IF analysis of N1E-115 using anti-PRG4 (1:500) Rabbit pAB (Red). Actin filaments have been labeled with Alexa Fluor 488 -Phalloidin (Green). Nuclear is stained with DAPI (Blue).

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Cat. # AB2220 recognizes PRG4.

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.

Stable for 1 year at 2-8ºC from date of receipt.

Control
Mouse Brain lysates

Western Blotting

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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