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AB3503-I

Anti-PDX-1 Antibody

Name: Anti-PDX-1 Antibody
Brand: MM

from rabbit, purified by affinity chromatography

Synonym(s):

Pancreas/duodenum homeobox protein 1, PDX-1, Glucose-sensitive factor, GSF, Insulin promoter factor 1, IPF-1, Insulin upstream factor 1, IUF-1, Islet/duodenum homeobox-1, IDX-1, Somatostatin-transactivating factor 1, STF-1

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC, WB

Citations:

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Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, human

technique(s)

immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

NP_000200

UniProt accession no.

P52945

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... PDX1(3651)

Description

General description

Pancreatic and duodenal homeobox 1, also known as PDX1, and Insulin promoter factor 1 is a human gene. This islet-specific protein activates transcription of the insulin andsomatostatin genes. It is a key regulator of islet peptide hormone expressionn and also plays an essential role in pancreatic development. Mutations in this gene may be involved in several disorders of the pancreas or in diabetes mellitus.

~38 kDa observed

Immunogen

KLH-conjugated linear peptide corresponding to region amino acids 90-120 of human PDX-1.

Application

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected pdx-1 in the islets of Langerhans of human and mouse pancreas.

This Anti-PDX-1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of PDX-1.

Biochem/physiol Actions

Recognizes PDX-1

Analysis Note

Evaluated by Western Blotting in mouse pancreatic beta cell tissue lysate.

Western Blotting Analysis: A 1:4,000 dilution of this antibody detected PDX-1 in mouse pancreatic beta cell tissue lysate.

Other Notes

Concentration: Please refer to lot specific datasheet.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c