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Merck
CN

AB5725

Anti-Gephyrin Antibody

Chemicon®, from rabbit

Synonym(s):

Anti-GEPH, Anti-GPH, Anti-GPHRYN, Anti-HKPX1, Anti-MOCODC

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Key Documents

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biological source

rabbit

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, rat

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

NM_001024218.1
NM_020806.4

UniProt accession no.

Q9NQX3

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... GPHN(10243)

Immunogen

Synthetic peptide from rat gephyrin.

Application

Anti-Gephyrin Antibody is an antibody against Gephyrin for use in WB.
Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
Western blot: 0.5-1.0 μg/mL using ECL on mouse cerebellum tissue lysate. The antibody reacts with a protein of ~93 kDa. An additional band of ~35 kDa may also be seen depending on sample used.

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Gephyrin

Physical form

Affinity purified immunoglobulin. Liquid.

Preparation Note

Maintain at +2-8°C in undiluted aliquots for up to 6 months after date of receipt.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Dibyadeep Datta et al.
Journal of neuroinflammation, 17(1), 8-8 (2020-01-08)
Cognitive impairment in schizophrenia, aging, and Alzheimer's disease is associated with spine and synapse loss from the dorsolateral prefrontal cortex (dlPFC) layer III. Complement cascade signaling is critical in driving spine loss and disease pathogenesis. Complement signaling is initiated by
Jessica S Nikitczuk et al.
Hippocampus, 24(8), 943-962 (2014-04-23)
N-Cadherin and β-catenin form a transsynaptic adhesion complex required for spine and synapse development. In adulthood, N-cadherin mediates persistent synaptic plasticity, but whether the role of N-cadherin at mature synapses is similar to that at developing synapses is unclear. To
Wen Zhou et al.
International journal of molecular medicine, 38(5), 1481-1489 (2016-12-28)
The medial vestibular nucleus (MVN) and the cerebellar flocculus have been known to be the key areas involved in vestibular compensation (VC) following unilateral labyrinthectomy (UL). In this study, we examined the role of gephyrin and glycine receptor (GlyR) in VC using Sprague-Dawley rats
Yvonne M Ulrich-Lai et al.
Brain structure & function, 221(6), 3141-3156 (2015-08-08)
A history of eating highly palatable foods reduces physiological and emotional responses to stress. For instance, we have previously shown that limited sucrose intake (4 ml of 30 % sucrose twice daily for 14 days) reduces hypothalamic-pituitary-adrenocortical (HPA) axis responses to stress. However

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