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ABS443

Sigma-Aldrich

Anti-ApoA5 Antibody

from rabbit, purified by affinity chromatography

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Synonym(s):
Apolipoprotein A5, ApoA-V
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

species reactivity (predicted by homology)

chicken (immunogen homology)

technique(s)

western blot: suitable

UniProt accession no.

E1BT17

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... APOA5(116519)

General description

Apolipoprotein A-V (ApoA5), also known as Apolipoprotein A5, is an apolipoprotein that plays an important role in regulating plasma triglyceride levels which is a major risk factor for coronary artery disease. ApoA5 is found in liver and plasma. Mutations in ApoA5 have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5.

Immunogen

KLH-conjugated linear peptide corresponding to chicken ApoA5.

Application

Anti-ApoA5 Antibody is a highly specific rabbit polyclonal antibody, that targets Apolipoprotein A & has been tested in western blotting.

Quality

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected ApoA5 in 15 µg of human liver tissue lysate.

Target description

~33 kDa observed

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Jinjie Wang et al.
International journal of molecular sciences, 20(14) (2019-07-22)
Familial hypercholesterolemia (FH) is a dominant inherited disease caused mainly by low-density lipoprotein receptor (LDLR) gene mutations. To different extents, both heterozygous and homozygous FH patients develop premature coronary heart disease (CHD). However, most of the experimental animal models with

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