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Merck
CN

CC1057

MMP-7, human, recombinant

Synonym(s):

Pro-matrilysin

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.77
eCl@ss:
32160405
Specific activity:
5453 U/mg
Assay:
~70% (followed by staining with CBB R-250, SDS-PAGE)
Biological source:
human
Concentration:
0.1 mg/mL

Key Documents

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biological source

human

assay

~70% (followed by staining with CBB R-250, SDS-PAGE)

form

liquid

specific activity

5453 U/mg

manufacturer/tradename

Chemicon®

concentration

0.1 mg/mL

NCBI accession no.

NM_002423.3

UniProt accession no.

P09237

shipped in

dry ice

General description

MOLECULAR WT:

28,924 Daltons calculated from primary amino acid sequence.
Product Source: Recombinant from E. Coli

Physical form

Solution in 25 mM Tris-HCl (pH 7.5), 5 mM CaCl2, 0.15 M NaCl, 0.01% Brij35 0.02% NaN3

Preparation Note

Maintain at -80ºC for up to one year from date of receipt.

Other Notes

Replaces: AG905
Specific Activity: One unit of enzyme activity is defined as the digestion of 1 micro g of Azocoll/min.at pH 7.5 and 37°C acetate.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Sergey Filippov et al.
The Journal of experimental medicine, 198(6), 925-935 (2003-09-10)
Human macrophages found in juxtaposition to fragmented elastin in vivo express the elastolytic matrix metalloproteinases (MMPs) progelatinase B, prometalloelastase, and promatrilysin. Though MMPs can degrade a range of extracellular matrix components, increasing evidence suggests that preferred targets in vivo include

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