Skip to Content
Merck
CN

Key Documents

View All Documentation

CHGE72TS3

Millipore Express® SHC 0.5/0.2µm Cartridge 20

Code 7 Silicone, Autoclavable and SIP

Synonym(s):

Millipore Express SHC Cartridge Filter 20 in. 0.5/0.2 μm Code 7 Silicone

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

UNSPSC Code:
23151806
eCl@ss:
32031690
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Millipore Express® SHC, Cartridge, Chemistry: 0.5 / 0.2 µm Hydrophilic Polyethersulfone (PES) Configuration: 20 in. Code 7

Quality Segment

400

material

polyethersulfone membrane, polypropylene housing, polypropylene support, silicone O-ring

reg. compliance

meets FDA Indirect Food Additive requirements cited in 21 CFR 177-182 (all component materials)

sterility

non-sterile

sterilization compatibility

autoclavable compatible
steam-in-place compatible

product line

Millipore Express®

feature

hydrophilic

manufacturer/tradename

Millipore Express®

parameter

0.34 bar max. differential pressure (5 psi) at 135 °C (Forward), 1 bar max. differential pressure (15 psi) at 135 °C (Forward), 1.7 bar max. differential pressure (25 psi) at 80 °C (Forward), 2.1 bar max. differential pressure (30 psi) at 25 °C (Reverse), 6.9 bar max. differential pressure (100 psi) at 25 °C (Forward), 69 mbar max. differential pressure (1 psi) at 135 °C (Reverse)

technique(s)

sterile filtration: suitable

L

20 in. (50.8 cm)

W

2.7 in.

cartridge nominal length

20 in. (50 cm)

diam.

13.8 cm (5.4 in.)

filtration area

0.98 m2

impurities

<0.25  EU/mL USP bacterial endotoxins (LAL test, sample aqueous extraction)

matrix

Millipore Express® SHC

pore size

0.5/0.2 μm pore size

bubble point

≥4000 mbar (58 psig), air with water at 23 °C

cartridge code

Code 7

General description

Millipore Express® SHC filters have an on-board polyethersulfone membrane prefilter which protects the 0.2 μm membrane from premature plugging and extends filtration capacity, so you get sterilizing-grade performance with superior throughput. The CHGE72TS3 cartridge filter features a 0.5/0.2 μm pore size, a filtration area of 0.98 m2 and a Code 7 cartridge configuration.

Millipore Express® SHC filters provide you with a single solution for a range of process fluids, minimizing validation efforts and simplifying filter inventory and stocking requirements. With Millipore Express® SHC filters, you increase productivity, shorten cycle-time and reduce cost.

Application

  • Media additives
  • Column protection
  • Concentrated protein streams
  • Cell harvest (post clarification)
  • Caustics/pH adjusters
  • Buffers
  • CIP solution

Features and Benefits

  • High capacity, high flux hydrophilic PES membranes
  • Validated sterilizing-grade performance
  • Easy wetting and integrity testing
  • Superior throughput in high fouling streams, including media and protein containing solutions
  • Increased capacity for improved process efficiency and economy
  • Broad chemical compatibility across a wide pH range (1-14) — caustic compatible

Packaging

Double Easy-Open bag

Preparation Note

Sterilization Method
25 forward or 22 forward and 3 reverse SIP cycles of 30 min @ 135 °C and 0.35 bar (5) or 3 forward SIP cycles of 30 min @ 135 °C and 1 bar (15 psid); 25 autoclave cycles of 60 min @ 126 °C
This product was manufactured with a Millipore Express membrane which meets the criteria for a "non-fiber releasing" filter as defined in 21 CFR 210.3 (b) (6).

Analysis Note

Bacterial Retention
Samples were quantitatively retentive of a minimum Brevundimonas diminuta challenge concentration of 1 x 10⁷ CFU/cm² using ASTM® F838 methodology.
TOC/Conductivity
After sterilization and a controlled water flush of 40 L, samples exhibited less than 500 ppb TOC per USP <64> and less than 1.3 µS/cm per USP <64> at 25 °C.
Will meet the USP Oxidizable Substances Test requirements after a water flush of ≥4 L

Other Notes

Directions for Use

  • Organism Retention: Microorganism
  • Mode of Action: Filtration (size exclusion)
  • Application: BioProcessing
  • Intended Use: Reduction or removal of microorganism/bioburden
  • Instructions for Use: Please refer wetting instructions of Filters with MILLIPORE EXPRESS® Membrane user guide
  • Storage Statement: Please refer Filters with MILLIPORE EXPRESS® Membrane user guide
  • Disposal Statement: Dispose of in accordance with applicable federal, state and local regulations.

These products are manufactured in a facility which adheres to FDA Good Manufacturing Practices.

Legal Information

ASTM is a registered trademark of American Society for Testing and Materials
MILLIPORE EXPRESS is a registered trademark of Merck KGaA, Darmstadt, Germany

Still not finding the right product?

Explore all of our products under Millipore Express® SHC, Cartridge

Stay compliant with GMP using the Emprove® Program

Accelerate qualification, maintain compliance, and save time with Emprove® Dossiers.

Download Dossiers

Note: you will be brought to EmproveSuite.com. Your username and password are separate from SigmaAldrich.com and may differ.

Register for free and access Emprove® Dossiers within minutes. Upgrade your subscription plan to unlock advanced and customized content in the Emprove® Suite

Not finding what you are looking for? Visit the Emprove® Program Help page.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library