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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
rat
conjugate
FITC conjugate
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
TC11-18H10.1, monoclonal
species reactivity
mouse
manufacturer/tradename
Milli-Mark®
technique(s)
flow cytometry: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
mouse ... Il17A(16171)
General description
17 kDa Calculated
IL17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL1beta, IL6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL17are significantly increased and may contribute to bone destruction.
Immunogen
Recombinant protein corresponding to mouse Il17a
Application
Milli-Mark Anti-Mouse IL-17 FITC Antibody, clone TC11-18H10.1 detects level of Mouse IL-17 & has been published & validated for use in FC.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Immunological Signaling
Immunological Signaling
Biochem/physiol Actions
Antibody recognizes Interleukin-17A.
Physical form
Antigen Affinity Purified
Purified rat monoclonal IgG1κ conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Preparation Note
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Analysis Note
Control
PMA and Ionomycin stimulated EL-4 cells.
PMA and Ionomycin stimulated EL-4 cells.
Evaluated by flow cytometry using stimulated EL-4 cells
Legal Information
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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