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Merck
CN

GF026

Granulocyte-Macrophage Colony-Stimulating Factor Protein, Recombinant mouse

The Granulocyte Macrophage Colony Stimulating Factor protein (GM-CSF protein) is a potent species specific stimulator of bone marrow cells.

Synonym(s):

GM-CSF

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About This Item

eCl@ss:
32160405
UNSPSC Code:
12352202

Key Documents

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Product Name

Granulocyte-Macrophage Colony-Stimulating Factor Protein, Recombinant mouse, The Granulocyte Macrophage Colony Stimulating Factor protein (GM-CSF protein) is a potent species specific stimulator of bone marrow cells.

biological source

mouse

assay

>98% (SDS-PAGE and HPLC)

specific activity

≥5 x 106 U/mg

manufacturer/tradename

Chemicon®

technique(s)

cell culture | mammalian: suitable

input

sample type hematopoietic stem cell(s)

NCBI accession no.

NM_000588.3

UniProt accession no.

P08700

shipped in

dry ice

Gene Information

mouse ... IL3(16187)

Analysis Note

Specific Activity: Chemicon′s mouse GM-CSF is fully biologically active when compared to standards.The ED50 as determined by the dose-dependent stimulation of the proliferation of mouse FDC-P1 cells in ≤ 0.2 ng/mL

Application

For most in vitro applications, murine GM-CSF exerts its biological activity in the concentration range of 0.05 to 0.5 ng/mL. Responding cells are (partial list): Certain BM precursor cells

General description

Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) is a potent species specific stimulator of bone marrow cells. GM-CSF stimulated precursor cells of granulocytes, macrophages, and eosinophils. Murine GM-CSF is a 14.0 kDa protein containing 124 amino acid residues.

Physical form

Sterile filtered solution lyophilized from 10mM HoAc.

Preparation Note

The lyophilized murine GM-CSF, though stable at room temperature, is best stored desiccated below 0°C. Reconstitute in water to a concentration of 100 ng/uL. This solution can be diluted into other buffered solutions. Reconstituted murine GM-CSF should be stored in working aliquots at -20°C.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

Certificates of Analysis (COA)

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