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Merck
CN

IM1012

Anti-MTA3 (400-450) Rabbit pAb

liquid, Calbiochem®

Synonym(s):

Anti-Metastasis-associated gene 3

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About This Item

UNSPSC Code:
12352203
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biological source

rabbit

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

isotype

IgG

shipped in

wet ice

storage temp.

2-8°C

Gene Information

human ... MTA3(57504)

General description

Immunoaffinity purified rabbit polyclonal antibody. Recognizes the ~62 kDa MTA3 protein.
Recognizes the ~62 kDa MTA3 protein in MCF-7 cells.
This Anti-MTA3 (400-450) Rabbit pAb is validated for use in Immunoblotting, Immunocytochemistry, Immunoprecipitation for the detection of MTA3 (400-450).

Immunogen

Human
a synthetic peptide corresponding to amino acids within residues 400-450 of human MTA3

Application



Immunoblotting (1:500-1:5000)
Immunocytochemistry (1:300)
Immunoprecipitation (2-10 g/mg lysate)

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In Tris-citrate/phosphate buffer, pH 7.0-8.0.

Preparation Note

Following initial use, aliquot and freeze (-20°C) for long-term storage.

Analysis Note

Positive Control
MCF7 cells

Other Notes

Antibody should be titrated for optimal results in individual systems.
Fujita, N., et. al. 2003. Cell113, 207.
Kumar R. 2003. Cell113, 142.
Simpson, A, et.al. 2001. Gene273, 29.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Highly Toxic (H)


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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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B Belinda Ding et al.
Journal of immunology (Baltimore, Md. : 1950), 190(4), 1827-1836 (2013-01-18)
After undergoing Ig somatic hypermutation and Ag selection, germinal center (GC) B cells terminally differentiate into either memory or plasma cells (PCs). It is known that the CD40L and IL-21/STAT3 signaling pathways play critical roles in this process, yet it
The metastasis-associated gene MTA3 is an independent prognostic parameter in uterine non-endometrioid carcinomas.
Ioannis Mylonas et al.
Histopathology, 60(4), 665-670 (2012-01-13)
Xin Yin et al.
Cell death and differentiation, 29(11), 2203-2217 (2022-05-10)
Runt-related transcription factor 2 (RUNX2) is an osteogenesis-related transcription factor that has emerged as a prominent transcription repressing factor in carcinogenesis. However, the role of RUNX2 in breast cancer metastasis remains poorly understood. Here, we show that RUNX2 recruits the