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Merck
CN

MAB10216

Anti-Flavivirus Group Antigen Antibody, clone D1-4G2-4-15

ascites fluid, clone D1-4G2-4-15, Chemicon®

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About This Item

eCl@ss:
32160702
UNSPSC Code:
12352203
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Product Name

Anti-Flavivirus Group Antigen Antibody, clone D1-4G2-4-15, ascites fluid, clone D1-4G2-4-15, Chemicon®

biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

D1-4G2-4-15, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable

isotype

IgG1
IgG2a

shipped in

dry ice

Application

Anti-Flavivirus Group Antigen Antibody, clone D1-4G2-4-15 detects level of Flavivirus Group Antigen & has been published & validated for use in IF.

Biochem/physiol Actions

Recognises flavivirus group specific antigens (Dengue virus, West Nile Virus, Japanese Encephalitis, Yellow Fever Virus, Zika virus etc). It binds to the fusion loop at the extremity of domain II of protein E.

General description

The viruses of the family Flaviviridae are important arthropod-borne viruses in both human and veterinary medicine. They are transmitted by mosquito and ticks and usually are maintained in a transmission cycle in nature. They produce a broad spectrum of clinical responses in humans ranging from asymptomatic infection to fulminant encephalitis or haemorrhagic fever. Nearly 60 flaviviruses are known to exist but many are yet to be shown to cause disease in humans.

Immunogen

Dengue virus type 2 antigens

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Marion Clé et al.
PLoS neglected tropical diseases, 14(4), e0008223-e0008223 (2020-04-24)
Usutu virus (USUV), an African mosquito-borne flavivirus closely related to West Nile virus, was first isolated in South Africa in 1959. USUV emerged in Europe two decades ago, causing notably massive mortality in Eurasian blackbirds. USUV is attracting increasing attention
Priya Luthra et al.
Antiviral research, 158, 288-302 (2018-08-26)
Specific host pathways that may be targeted therapeutically to inhibit the replication of Ebola virus (EBOV) and other emerging viruses remain incompletely defined. A screen of 200,000 compounds for inhibition of an EBOV minigenome (MG) assay that measures the function
Himanshu Garg et al.
Scientific reports, 10(1), 4017-4017 (2020-03-07)
Mosquito borne viral diseases are an emerging threat as evident from the recent outbreak of Zika virus (ZIKV) as well as repeated outbreaks of Chikungunya (CHIKV), Yellow fever (YFV) and Japanese encephalitis (JEV) virus in different geographical regions. These four
Jean A Bernatchez et al.
Antimicrobial agents and chemotherapy, 62(10) (2018-08-01)
Zika virus (ZIKV) has been linked to the development of microcephaly in newborns, as well as Guillain-Barré syndrome. There are currently no drugs available to treat ZIKV infection, and accordingly, there is an unmet medical need for the discovery of
Pawan Kumar Singh et al.
The ocular surface, 17(3), 551-559 (2019-03-25)
Zika virus (ZIKV) has emerged as an important human pathogen causing ocular complications. There have been reports of the shedding of ZIKV in human as well as animal tears. In this study, we investigated the infectivity of ZIKV in corneal

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