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Merck
CN

MAB3126

Anti-Calnexin Antibody, ER marker, clone C8.B6

ascites fluid, clone C8.B6, Chemicon®

Synonym(s):

IP90 Protein, Integral Membrane Protein IP90, Phosphoprotein pp90

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

C8.B6, monoclonal

species reactivity

mouse, human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Quality Level

Gene Information

human ... CANX(821)

General description

Calnexin is a Ca++ binding protein found in endoplasmic reticulum membranes that binds to specific n-linked oligosaccharides found on newly synthesized proteins. It may play role in protein folding or retention and degradation of misfolded proteins in the endoplasmic reticulum.

Immunogen

Epitope: ER marker
Recombinant human calnexin

Application

Detect Calnexin using this Anti-Calnexin Antibody, ER marker, clone C8.B6 validated for use in IC, IH, IP & WB.
Immunohistochemistry on frozen tissue sections: 1:500-1:2,000

Immunocytochemistry: 1:100--1:250

Immunoblotting: 1:200-1:2,000

Immunoprecipitation: 1:200-1:1,000

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Recognizes Calnexin.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10-13 - German Storage Class 10 to 13


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Zumhagen, S; Veldkamp, MW; Stallmeyer, B; Baartscheer, A; Eckardt, L; Paul, M; Remme et al.
Testing null
Stephen DiGiuseppe et al.
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Rossella Titone et al.
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Insulin and insulin-like growth factor-1 (IGF-1) are present in human tears and likely play an important role in mediating ocular surface homeostasis. We previously characterized the IGF-1/insulin hybrid receptor (Hybrid-R) in corneal epithelial cells and found that it was activated

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