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Merck
CN

MAB3773

Anti-Annexin I Antibody, clone 6E4/3

clone 6E4/3, Chemicon®, from mouse

Synonym(s):

Lipocortin I, Calpactin II, Chromobindin 9, Phospholipase A2 Inhibitory Protein

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Key Documents

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biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

6E4/3, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunofluorescence: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_000700.1

UniProt accession no.

P04083

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ANXA1(301)

General description

Annexin I belongs to a family of Ca2+ dependent phospholipid binding proteins. It has been implicated in the regulation of phagocytosis, cell signaling and cell proliferation.

Immunogen

Whole native annexin proteins contained in a mixture of membrane proteins from human bone tissue

Application

Anti-Annexin I Antibody, clone 6E4/3 detects level of Annexin I & has been published & validated for use in ELISA, IF & WB.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Western blot

Immunofluorescence

ELISA

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Recognizes human Annexin I

Physical form

Format: Purified
Purified immunoglobulin. Liquid in 0.02M phosphate buffer, 0.25M NaCl, pH 7.6, with 0.1% sodium azide

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Wanying Miao et al.
Journal of immunology (Baltimore, Md. : 1950), 204(6), 1486-1498 (2020-02-09)
Microglia play essential roles in neuroinflammatory responses after traumatic brain injury (TBI). Our previous studies showed that phenotypes of microglia, as well as infiltrating macrophages, altered at different stages after CNS injury, which was correlated to functional outcomes. IL-13 is
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Nephron, 139(1), 70-82 (2018-02-07)
Previous studies showed that ceftriaxone can cause acute kidney injury (AKI) in the pediatric population. This study proposed a cellular model of crystalline nephropathy in ceftriaxone-associated AKI and explored the related pathophysiology by using a proteomic approach. Ceftriaxone was crystallized

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