MAB858-2
Anti-RSV Antibody, glycoprotein, all type A, B strains, clone 131-2G
clone 131-2G, from mouse
Synonym(s):
RSV
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
131-2G, monoclonal
Species reactivity:
human
Application:
ELISA, IF
Citations:
23
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
131-2G, monoclonal
species reactivity
human
Quality Level
technique(s)
ELISA: suitable, immunofluorescence: suitable
isotype
IgG1κ
shipped in
wet ice
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General description
RSV is a labile paramyxovirus that produces a characteristic fusion of human cells in tissue culture--the syncytial effect. Two subtypes, A and B, have been identified. Subtype B are characterized as the asymptomatic strains of the virus. The more severe clinical illnesses involve Subtype A strains.
Immunogen
A2
Epitope: some type B strains
Application
Detect Respiratory Syncytial Virus using this Anti-RSV Antibody, glycoprotein, all type A, B strains, clone 131-2G validated for use in ELISA & IF.
ELISA
Indirect Immunofluorescence (fresh frozen tissue sections)
Final working dilutions must be determined by end user.
Indirect Immunofluorescence (fresh frozen tissue sections)
Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
Biochem/physiol Actions
Glycoprotein, 89 kD. Recognizes both A and B strains.
Physical form
Format: Purified
Purified immunoglobulin. 1 mg/mL in 0.02M PB with 0.25M NaCl, pH=7.6 containing 0.1% sodium azide.
Preparation Note
Maintain at 2 to 8° C in aliquots for up to 12 months after date of receipt. Do not store in diluted format.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Myra N Widjojoatmodjo et al.
Virology journal, 7, 114-114 (2010-06-08)
Respiratory syncytial virus (RSV) is a primary cause of serious lower respiratory tract illness for which there is still no safe and effective vaccine available. Using reverse genetics, recombinant (r)RSV and an rRSV lacking the G gene (DeltaG) were constructed
Exploratory Spatial Analysis of in vitro Respiratory Syncytial Virus Co-infections.
Simeonov, I; Gong, X; Kim, O; Poss, M; Chiaromonte, F; Fricks, J
Viruses null
Edgar R Wood et al.
The Journal of biological chemistry, 290(32), 19681-19696 (2015-06-10)
2',5'-Oligoadenylate synthetase (OAS) enzymes and RNase-L constitute a major effector arm of interferon (IFN)-mediated antiviral defense. OAS produces a unique oligonucleotide second messenger, 2',5'-oligoadenylate (2-5A), that binds and activates RNase-L. This pathway is down-regulated by virus- and host-encoded enzymes that
Bo Liang et al.
Journal of virology, 93(7) (2019-01-18)
Human respiratory syncytial virus (RSV) is a major pediatric respiratory pathogen. The attachment (G) and fusion (F) glycoproteins are major neutralization and protective antigens. RSV G is expressed as membrane-anchored (mG) and -secreted (sG) forms, both containing a central fractalkine-like
Rachel J Derscheid et al.
Viruses, 5(11), 2881-2897 (2013-11-29)
Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis in infants and young children. A small percentage of these individuals develop severe and even fatal disease. To better understand the pathogenesis of severe disease and develop therapies unique
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