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Merck
CN

MABC1720

Anti-PMEL Antibody, clone HMB-45

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Species reactivity:
human, mouse
Conjugate:
unconjugated
Application:
IHC
Citations:
-
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conjugate

unconjugated

antibody form

purified antibody

clone

HMB-45, monoclonal

purified by

using protein G

species reactivity

human, mouse

concentration

(Please refer to lot specific datasheet.)

technique(s)

immunohistochemistry: suitable

isotype

IgG1κ

UniProt accession no.

target post-translational modification

unmodified

General description

70.25 kDa calculated.
Pigmented melanoma metastases extracted from human lymph nodes.

Application

Immunohistochemistry (Paraffin) Analysis: A 1:250 dilution from a representative lot detected PMEL in human melanoma tissue sections.

Immunohistochemistry (Paraffin) Analysis: A representative lot detected PMEL in Immunohistochemistry applications (Gown, A.M., et. al. (1986). Am J Pathol. 123(2):195-203).

Biochem/physiol Actions

Clone HMB-45 is a mouse monoclonal antibody that detects human Melanocyte protein PMEL.

Physical form

Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Immunohistochemistry (Paraffin) in human skin tissue sections.

Immunohistochemistry (Paraffin) Analysis: A 1:250 dilution of this antibody detected PMEL in human skin tissue sections.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


Regulatory Information

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Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
MABC1720-25UG04054839007217
MABC1720-100UG04054839007200