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Merck
CN

MABF2233

Sigma-Aldrich

Anti-West Nile Virus Antibody, clone E60

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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conjugate

unconjugated

antibody form

purified antibody

clone

E60
monoclonal

purified by

using protein G

species reactivity

virus, mouse

concentration

(Please refer to lot specific datasheet.)

technique(s)

immunocytochemistry: suitable
western blot: suitable

isotype

IgG2aκ

capacity

neutralization

UniProt accession no.

target post-translational modification

unmodified

General description

West Nile Virus envelope protein.
~47 kDa observed; 31.88 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Application

Immunocytochemistry Analysis: A representative lot detected West Nile Virus in Immunocytochemistry applications (Johnson, B., et. al. (2018). Immunity. 48(3):487-499).

Neutralizing Analysis: A representative lot partially neutralized West Nile Virus infection. (Oliphant, T., et. al. (2006). J Virol. 80(24):12149-59; Thompson, B.S., et. al. (2009). PLoS Pathog. 5(5):e1000453).

Biochem/physiol Actions

Clone E60 is a mouse monoclonal antibody that specifically detects envelope protein of West Nile Virus. It targets an epitope within the DII fusion loop.

Physical form

Purified mouse monoclonal antibody IgG2a in PBS without azide.

Preparation Note

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Analysis Note

Evaluated by Western Blotting with full-length ectodomain of West nile virus envelope protein.

Western Blotting Analysis: 1 µg/mL of this antibody detected full-length ectodomain of West nile virus envelope protein.

Other Notes

Virus (West Nile Virus).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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