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Merck
CN

MABN2320

Sigma-Aldrich

Anti-TREM-2 Antibody, C-terminal Antibody, clone 14D1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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conjugate

unconjugated

antibody form

purified antibody

clone

14D1
monoclonal

purified by

using protein G

species reactivity

mouse, rat, mouse

concentration

(Please refer to lot specific datasheet.)

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG2aκ

UniProt accession no.

target post-translational modification

unmodified

General description

24.53 kDa calculated.
A linear peptide corresponding to 20 amino acids from the C-terminal region of murine Triggering receptor expressed on myeloid cells 2 (TREM-2).

Application

Immunohistochemistry (Paraffin) Analysis: A 1:25 dilution from a representative lot detected TREM-2 in mouse cerebral cortex and olfactory lobe tissue sections.

Western Blotting Analysis: A representative lot detected TREM-2 in Western Blotting applications (Kleinberger, G., et. al. (2017). EMBO J. 36(13):1837-1853).

Biochem/physiol Actions

Clone 14D1 is a rat monoclonal antibody that specifically detects murine Triggering receptor expressed on myeloid cells 2 (TREM-2). It targets an epitope with in 20 amino acids from the C-terminal region.

Physical form

Purified rat monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Immunohistochemistry (Paraffin) in mouse hindbrain tissue sections.

Immunohistochemistry (Paraffin) Analysis: A 1:25 dilution of this antibody detected TREM-2 in mouse hindbrain tissue sections.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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