Solute carrier family 22 member 3 (UniProt O75751; also known as EMT, Extraneuronal monoamine transporterorganic cation transporter 3, Organic cation transporter 3) is encoded by the SLC22A3 (also known as EMTH, OCT3) gene (Gene ID 6581) in human. Solute carrier family 22 member 3 is a multi-transmembrane protein that mediates the outward transport and clearance of endogenous small organic cations as well as a wide array of drugs and environmental toxins. Known substrates for this transporter include histamine, serotonin, norepinephrine, dopamine and MPP+.

~70 kDa observed. Due to glycosylation, the target band appears larger than the calculated molecular weight of 61.3 kDa

Epitope: C-terminal

GST-tagged recombinant protein corresponding to the C-terminal of human SLC22A3.

Anti-SLC22A3 Antibody, clone 4H6.1, Cat. No. MABN359, is a highly specific mouse monoclonal antibody, that targets SLC22A3 and has been tested in Western Blotting.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Evaluated by Western Blotting in human brain tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected SLC22A3 in 10 µg of human brain tissue lysate.

Concentration: Please refer to lot specific datasheet.

Replaces: MABN1039

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