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Merck
CN

MABS2188

Sigma-Aldrich

Anti-SIRP alpha Antibody, clone SAF10.1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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conjugate

unconjugated

antibody form

purified antibody

clone

SAF10.1
monoclonal

purified by

using protein G

species reactivity

human, mouse, human

concentration

(Please refer to lot specific datasheet.)

technique(s)

ELISA: suitable
western blot: suitable

isotype

IgG1κ

UniProt accession no.

target post-translational modification

unmodified

General description

Eukaryotically expressed SIRP-Fc fusion protein consisting of the extracellular domain.
~75 kDa observed; 54.97 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Application

Western Blotting Analysis: 1 µg/mL from a representative lot detected SIRP alpha in A549 cell lysate.

Western Blotting Analysis: A represetntative lot detected SIRP alpha in Western Blotting applications (Lee, W.Y., et. al. (2007). J. Immunol. 179(11); 7741-50).

ELISA Analysis: A represetntative lot detected SIRP alpha in ELISA applications (Lee, W.Y., et. al. (2007). J. Immunol. 179(11); 7741-50).

Biochem/physiol Actions

Clone SAF10.1 is a mouse monoclonal antibody that detects human Tyrosine-protein phosphatase non-receptor type substrate 1 (SIRP alpha). It targets an epitope in the membrane most distal domain (D1).

Physical form

Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in U20S cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected SIRP alpha in U20S cell lysate.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Regulatory Information

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