Merck
CN

P3C030C01

Millipore

Pellicon® 3 Cassette with Ultracel® Membrane

filtration area 0.11 m2, NMWCO 30 kDa

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Synonym(s):
Pellicon® 3 Cassette with Ultracel 30 kDa Membrane, C screen, 0.11 m2
eCl@ss:
32031602

material

TPE seal
composite regenerated cellulose (CRC)
polypropylene cap (for end)
polypropylene screen

Quality Level

feature

holdup volume 18 mL (in feed channel)

manufacturer/tradename

Pellicon®

parameter

30 psi max. reverse press. exposure at 25 °C (for 24 hours)
4-6 L/min-m2 recirculation rate
40 psi max. transmembrane pressure at 4-50 °C
6.9 bar max. inlet pressure (100 psi)
80 psi max. transmembrane pressure at 4-40 °C

technique(s)

analytical sample preparation: suitable
buffer exchange: suitable
protein purification: suitable (concentration)

H

2.3 cm (0.90 in.)

L

20.6 cm (8.1 in.)

W

5.6 cm (2.2 in.)

filtration area

0.11 m2

membrane area

0.11 m2

gravimetric extractables

≤1500 mg/m2

matrix

Ultracel® (Membrane)

pore size

30 kDa NMWCO

pH

2-13

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General description

Pellicon® 3 filtration devices are advanced, high-performance cassettes ideal for today’s higher titer therapeutic antibodies as well as the more demanding filtration processes that require higher operating pressures, temperatures and caustic cleaning regimes.

The Pellicon® 3 Cassette with Ultracel® Membrane is designed for the filtration of therapeutic proteins (such as monoclonal antibodies) and recombinant and non-recombinant proteins.

This P3C030C01 Pellicon® 3 ultrafiltration device features a pore size of 30 kDa NMWCO, a filtration area of 0.11 m2, a PLCTK membrane, and dimensions measuring 0.8 cm (H) x 5.6 cm (W) x 20.6 cm (L).

Features and Benefits

  • Rugged & reliable – ideally suited for today′s more demanding filtration processes
  • High performance – produces excellent resolution, yields and back-pressure resistance
  • Optimum product recovery – thanks to proven membrane technology
  • Void-free technology – leading-edge membranes resolve virtually any separation challenge
  • Defect-free, superior adhesion – Ultracel®uses composite membranes cast on a microporous substrate
  • Automated manufacturing – delivers unbeatable performance, consistency and reliability
  • Easy installation & care – simple to install and maintain

Other Notes

These products are manufactured in a facility which adheres to Good Manufacturing Practices.

Analysis Note

Gravimetric Extractables: after 24 hours in water at controlled room temperature

Legal Information

Pellicon is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTRACEL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

WGK

WGK 1


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Articles

Find best practices for using Pellicon® Capsules in ADC processing as well as data from two studies using Pellicon® Capsules and Pellicon® cassettes in the ADC manufacturing process.

Get practical guidance on using single-pass tangential flow filtration in your downstream process and scaling between capsules and cassettes.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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