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11093037001

Roche

Chromozym t-PA

powder, 90% (enzymatic), 0.25 mM

Synonym(s):

N-Methylsulfonyl-D-Phe-Gly-Arg-4-nitranilide acetate

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About This Item

UNSPSC Code:
12352204
NACRES:
NA.54
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assay

90% (enzymatic)

form

powder

mol wt

636.7

packaging

pkg of 20 mg

manufacturer/tradename

Roche

concentration

0.25 mM

storage temp.

20-25°C

General description

N-Methylsulfonyl-D-Phe-Gly-Arg-4-nitranilide acetate

Application

Use Chromozym® t-PA (tissue plasminogen activator) (C24H32N8O7S x CH3COOH) as a substrate for the determination of t-PA, both in purified preparations and in cell culture supernatants. Moreover, it can be applied to evaluate the content of one-chain and two-chain t-PA.

Preparation Note

Working concentration: Approximately 0.25 mM
Storage conditions (working solution): 2 to 8 °C
An aqueous solution of Chromozym t-PA (4mM) is stable for at least two weeks if stored at 2 to 8 °C.

Analysis Note

Purity: >90% (enzymatic)
Contaminant: <0.5% free 4-nitraniline

Other Notes

For life science research only. Not for use in diagnostic procedures.
N-Methylsulfonyl-D-Phe-Gly-Arg-4-nitranilide-acetate

Legal Information

Chromozym is a registered trademark of Pentapharm AG, Basel

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number
76693323
69927620
69335920
66136321
66136320

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Lucia Cilenti et al.
The Journal of biological chemistry, 278(13), 11489-11494 (2003-01-17)
Omi/HtrA2 is a mammalian serine protease with high homology to bacterial HtrA chaperones. Omi/HtrA2 is localized in mitochondria and is released to the cytoplasm in response to apoptotic stimuli. Omi/HtrA2 induces cell death in a caspase-dependent manner by interacting with

Global Trade Item Number

SKUGTIN
1109303700104061838698414