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Merck
CN

01-6635

Sigma-Aldrich

Arsenic(III) oxide

SAJ first grade, ≥99.0%

Synonym(s):

Arsenic trioxide, Arsenous acid

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About This Item

Empirical Formula (Hill Notation):
As2O3
CAS Number:
1327-53-3
Molecular Weight:
197.84
EC Number:
215-481-4
MDL number:
MFCD00003433
UNSPSC Code:
12352103
PubChem Substance ID:
329747341

Key Documents

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grade

SAJ first grade

vapor pressure

0.000001 hPa ( 66 °C)

Assay

≥99.0%

form

powder

availability

available only in Japan

SMILES string

O=[As]O[As]=O

InChI

1S/As2O3/c3-1-5-2-4

InChI key

IKWTVSLWAPBBKU-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Statements

H300,H314,H350,H372,H410

Hazard Classifications

Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Skin Corr. 1B - STOT RE 1

Target Organs

Respiratory system,Cardio-vascular system,Gastrointestinal tract

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
U8343
U2522

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Lauren A Held et al.
Cancer investigation, 31(3), 172-176 (2013-02-15)
This Phase I study assessed the feasibility of concomitant arsenic trioxide (ATO), ascorbic acid (AA), and bortezomib (Velcade™) (AAV) for patients with relapsed/refractory multiple myeloma. ATO (0.25 mg/kg) and AA (1 g) were given with an escalating dose of bortezomib
Angela M Mitchell et al.
Journal of virology, 87(8), 4571-4583 (2013-02-15)
Interactions with cellular stress pathways are central to the life cycle of many latent viruses. Here, we utilize adeno-associated virus (AAV) as a model to study these interactions, as previous studies have demonstrated that cellular stressors frequently increase transduction of
Athena Kritharis et al.
Annals of hematology, 92(6), 719-730 (2013-03-16)
For more than 2,000 years, arsenic and its derivatives have shown medical utility. Owing to the toxicities and potential carcinogenicity of arsenicals, their popularity has fluctuated. The exact mechanism of action of therapeutic arsenic is not well characterized but likely
Huihui Wang et al.
Environmental toxicology, 28(5), 267-275 (2013-04-17)
Although arsenic is effective in the treatment of acute promyelocytic leukemia (APL), as a well-known environmental toxicant, the side effects of arsenic treatment and arsenic methylation metabolism of the patients are rarely reported. In this manuscript, we investigated 23 APL
Hong Li et al.
Croatian medical journal, 54(1), 12-16 (2013-02-28)
To investigate the role of tumor apoptosis-inhibitory protein survivin in arsenic trioxide-induced apoptosis in VX-2 carcinoma in the rabbit liver by means of transcatheter arterial chemoembolization. Sixteen rabbits with 32 implanted hepatic VX-2 tumors were randomly divided into two groups.
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