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Merck
CN

24-1560

Phenothiazine

SAJ first grade

Synonym(s):

10H-Phenothiazine

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About This Item

Empirical Formula (Hill Notation):
C12H9NS
CAS Number:
92-84-2
Molecular Weight:
199.27
EC Number:
202-196-5
UNSPSC Code:
12352005
PubChem Substance ID:
329752589
Beilstein/REAXYS Number:
143237
MDL number:
MFCD00005015
Grade:
SAJ first grade
Bp:
371 °C (lit.)

Key Documents

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InChI key

WJFKNYWRSNBZNX-UHFFFAOYSA-N

InChI

1S/C12H9NS/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H

SMILES string

N1c2ccccc2Sc3ccccc13

grade

SAJ first grade

availability

available only in Japan

dilution

(for analytical testing)

bp

371 °C (lit.)

mp

182-187 °C (lit.)

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signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1 - STOT RE 2 Oral

target_organs

Blood

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
U2891
U2179
U4432
U2685
A9243

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Tatsuya Hoshino et al.
Bioelectrochemistry (Amsterdam, Netherlands), 84, 1-5 (2011-10-07)
We report on a novel fabrication approach of amperometric biosensor based on multilayer films containing carbon nanotubes (CNT), a nano-thin plasma-polymerized film (PPF), electron transfer mediator phenothiazine (PT), and enzyme glucose dehydrogenase (GDH). The configuration of the electrochemical electrode is
Thankamoniamma Manju et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 11(11), 1744-1755 (2012-09-04)
The reaction pathways following electronic excitation of 10-methyl phenothiazine (MPS) in the presence of oxygen have been investigated as a contribution to establish the mechanisms involved in the phototoxic reactions related to phenothiazine drugs. In the context of previously published
S C Mitchell
Current drug targets, 7(9), 1181-1189 (2006-10-05)
Phenothiazine is an aromatic tricyclic compound that first emerged from the furtive chemical activity surrounding the aniline dye industry at the latter half of the 19th century. It contains both nitrogen and sulphur atoms and is the parent molecule of
Mechanistic basis of phenothiazine-driven inhibition of Tau aggregation.
Elias Akoury et al.
Angewandte Chemie (International ed. in English), 52(12), 3511-3515 (2013-02-13)
Maike J Ohlow et al.
Drug discovery today, 16(3-4), 119-131 (2011-01-18)
Rooted in the early days of organic dye chemistry, the phenothiazine structure and its derivatives have since held a prominent place in pharmacology and biomedicine. Initially used for histochemical stains of plasmodia by Paul Ehrlich, anthelmintic and antibiotic properties of
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